Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Sep 28:2:203.
doi: 10.3389/fmicb.2011.00203. eCollection 2011.

Acquired antibiotic resistance genes: an overview

Angela H A M van Hoek  1 , Dik Mevius, Beatriz Guerra, Peter Mullany, Adam Paul Roberts, Henk J M Aarts
Affiliations

Acquired antibiotic resistance genes: an overview

Angela H A M van Hoek et al. Front Microbiol. .

Abstract

In this review an overview is given on antibiotic resistance (AR) mechanisms with special attentions to the AR genes described so far preceded by a short introduction on the discovery and mode of action of the different classes of antibiotics. As this review is only dealing with acquired resistance, attention is also paid to mobile genetic elements such as plasmids, transposons, and integrons, which are associated with AR genes, and involved in the dispersal of antimicrobial determinants between different bacteria.

Keywords: acquired; antibiotics; antimicrobial resistance mechanisms; mobile genetic elements.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. Aarestrup F. M. (1995). Occurrence of glycopeptide resistance among Enterococcus faecium isolates from conventional and ecological poultry farms. Microb. Drug Resist. 1, 255–25710.1089/mdr.1995.1.255 - DOI - PubMed
    1. Aarestrup F. M., Jensen N. E. (1998). Development of penicillin resistance among Staphylococcus aureus isolated from bovine mastitis in Denmark and other countries. Microb. Drug Resist. 4, 247–25610.1089/mdr.1998.4.307 - DOI - PubMed
    1. Abraham E. P., Chain E. (1940). An enzyme from bacteria able to destroy penicillin. Nature 146, 837.10.1038/146837b0 - DOI - PubMed
    1. Ackermann G., Rodloff A. C. (2003). Drugs of the 21st century: telithromycin (HMR 3647) – the first ketolide. J. Antimicrob. Chemother. 51, 497–51110.1093/jac/dkg113 - DOI - PubMed
    1. Adrian P. V., Thomson C. J., Klugman K. P., Amyes S. G. B. (2000). New gene cassettes for trimethoprim resistance, dfr13, and streptomycin-spectinomycin resistance, aadA4, inserted on a class 1 integron. Antimicrob. Agents Chemother. 44, 355–36110.1128/AAC.44.3.732-738.2000 - DOI - PMC - PubMed