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. 2011;6(10):e26881.
doi: 10.1371/journal.pone.0026881. Epub 2011 Oct 26.

Population attributable risk of unintentional childhood poisoning in Karachi Pakistan

Bilal Ahmed  1 , Zafar Fatmi, Amna R Siddiqui
Affiliations

Population attributable risk of unintentional childhood poisoning in Karachi Pakistan

Bilal Ahmed et al. PLoS One. 2011.

Abstract

Background: The percentage of unintentional childhood poisoning cases in a given population attributable to specific risk factors (i.e., the population attributable risk) which can be calculated; determination of such risk factors associated with potentially modifiable risk factors, are necessary to focus on the prevention strategies.

Methods: We calculated PARs, using 120 cases with unintentional poisoning and 360 controls in a hospital based matched case- control study. The risk factors were accessibility to hazardous chemicals and medicines due to unsafe storage, child behavior reported as hyperactive, storage of kerosene and petroleum in soft drink bottles, low socioeconomic class, less education of the mother and the history of previous poisoning.

Results: THE FOLLOWING ATTRIBUTED RISKS WERE OBSERVED: 12% (95% confidence interval [CI] = 8%-16%) for both chemicals and medicines stored unsafe, 19% (15%-23%) for child reported as hyperactive, 40% (38%-42%) for storage of kerosene and petroleum in soft drink bottles, 48% (42%-54%) for low socioeconomic status, 38% (32%-42%) for no formal mothers education and 5.8% (2%-10%) for history of previous poisoning. 48% of cases for overall study population which could be attributed to at least one of the six risk factors. Among girls, this proportion was 23% and 43% among boys. About half of the unintentional childhood poisoning cases in this Pakistani population could be avoided.

Conclusion: Exposure to potentially modifiable risk indicators explained about half of the cases of unintentional poisoning among children under five years of age in this Pakistani population, indicating the theoretical scope for prevention of the disease.

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Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

References

    1. Bronstein AC, Spyker DA, Cantilena LR., Jr 2007 Annual Report of the American Association of Poison Control Centers' National Poison Data System (NPDS): 25th Annual Report. Clinical Toxicology. 2008;46(10):927–1057. - PubMed
    1. Hyder AA, Wali S, Fishman S, Schenk E. The burden of unintentional injuries among the under-five population in South Asia. Acta Paediatrica. 2008;97(3):267–275. - PubMed
    1. Peden M MK, Sharma G. Geneva: World Health Organization; 2002. The a graphical overview of - The Injury Chart Book: A graphical overview of the global burden of injuries.
    1. Franklin RL, Rodgers GB. Unintentional Child Poisonings Treated in United States Hospital Emergency Departments: National Estimates of Incident Cases, Population-Based Poisoning Rates, and Product Involvement. Pediatrics. 2008;122(6):1244–1251. - PubMed
    1. O'Brien CW. Bethesda, MD: US Consumer Product Safety Commission; 2008. Pediatric Poisoning Fatalities From 1972 Through 2005.