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Practice Guideline
. 2012 Jan;13(1):e11-22.
doi: 10.1016/S1470-2045(11)70175-9. Epub 2011 Oct 31.

Recommendations for liver transplantation for hepatocellular carcinoma: an international consensus conference report

Pierre-Alain Clavien  1 , Mickael Lesurtel, Patrick M M Bossuyt, Gregory J Gores, Bernard Langer, Arnaud Perrier; OLT for HCC Consensus Group
Collaborators, Affiliations
Practice Guideline

Recommendations for liver transplantation for hepatocellular carcinoma: an international consensus conference report

Pierre-Alain Clavien et al. Lancet Oncol. 2012 Jan.

Abstract

Although liver transplantation is a widely accepted treatment for hepatocellular carcinoma (HCC), much controversy remains and there is no generally accepted set of guidelines. An international consensus conference was held on Dec 2-4, 2010, in Zurich, Switzerland, with the aim of reviewing current practice regarding liver transplantation in patients with HCC and to develop internationally accepted statements and guidelines. The format of the conference was based on the Danish model. 19 working groups of experts prepared evidence-based reviews according to the Oxford classification, and drafted recommendations answering 19 specific questions. An independent jury of nine members was appointed to review these submissions and make final recommendations, after debates with the experts and audience at the conference. This report presents the final 37 statements and recommendations, covering assessment of candidates for liver transplantation, criteria for listing in cirrhotic and non-cirrhotic patients, role of tumour downstaging, management of patients on the waiting list, role of living donation, and post-transplant management.

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Conflict of interest statement

Conflicts of interest

The authors declared no conflicts of interest.

Figures

Figure 1
Figure 1. Format of the HCC consensus conference
The role of the organising committee, expert groups, and jury at each step of the conference. HCC=hepatocellular carcinoma. GRADE=grading of recommendations assessment, development, and evaluation.
See this image and copyright information in PMC

References

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    1. Lesurtel M, Clavien PA. 2010 international consensus conference on liver transplantation for hepatocellular carcinoma: texts of experts. Liver Transpl. 2011;17(suppl 2):S1–S5. - PubMed

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