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Review
. 1990 Mar-Apr;63(2):173-82.

Modulation of host defense by the neuropeptide alpha-MSH

J M Lipton  1
Affiliations
Review

Modulation of host defense by the neuropeptide alpha-MSH

J M Lipton. Yale J Biol Med. 1990 Mar-Apr.

Abstract

alpha-melanocyte stimulating hormone (alpha-MSH), a peptide that occurs within the brain, the circulation, and other body sites, is a potent antipyretic agent when given centrally or peripherally. The peptide likewise inhibits inflammation and aspects of the acute-phase response. The combined evidence suggests that alpha-MSH molecules act as natural modulators of host reactions by antagonizing the central and peripheral actions of cytokines.

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References

    1. J Immunol. 1986 Oct 1;137(7):2232-6 - PubMed
    1. J Immunol. 1988 Jun 15;140(12):4300-7 - PubMed
    1. J Rheumatol. 1985 Oct;12(5):971-5 - PubMed
    1. Proc Natl Acad Sci U S A. 1981 Dec;78(12):7530-4 - PubMed
    1. Peptides. 1982 May-Jun;3(3):353-95 - PubMed

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