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Review
. 2012:7:385-422.
doi: 10.1146/annurev-pathol-011811-132448. Epub 2011 Nov 4.

Psoriasis

Gayathri K Perera  1 , Paola Di Meglio, Frank O Nestle
Affiliations
Review

Psoriasis

Gayathri K Perera et al. Annu Rev Pathol. 2012.

Abstract

Psoriasis is a common relapsing and remitting immune-mediated inflammatory disease that affects the skin and joints. This review focuses on current immunogenetic concepts, key cellular players, and axes of cytokines that are thought to contribute to disease pathogenesis. We highlight potential therapeutic targets and give an overview of the currently used immune-targeted therapies.

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