Another "loophole" in miRNA processing
- PMID: 22055181
- DOI: 10.1016/j.molcel.2011.10.010
Another "loophole" in miRNA processing
Abstract
In this issue of Molecular Cell, Suzuki et al. (2011) present the intriguing finding that an RNAse known to play an important role in immunity regulates miRNA processing in cancer and inflammation by cleaving the terminal loops of many miRNAs.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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MCPIP1 ribonuclease antagonizes dicer and terminates microRNA biogenesis through precursor microRNA degradation.Mol Cell. 2011 Nov 4;44(3):424-36. doi: 10.1016/j.molcel.2011.09.012. Mol Cell. 2011. PMID: 22055188
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