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. 1990 Oct;162(4):974-7.
doi: 10.1093/infdis/162.4.974.

Age-specific prevalence of antibody to enterotoxigenic Escherichia coli in Ecuadorian and German children

H Brüssow  1 , J Sidoti, H Link, Y K Hoang, D Barclay, H Dirren, W B Freire
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Age-specific prevalence of antibody to enterotoxigenic Escherichia coli in Ecuadorian and German children

H Brüssow et al. J Infect Dis. 1990 Oct.

Abstract

Serum samples from 1397 Ecuadorian children 0-5 years of age were tested by ELISA for antibodies to enterotoxigenic Escherichia coli (ETEC). A gradual prevalence and titer increase was seen for IgG antibodies to heat-labile enterotoxin in children 6-18 months old; 90% prevalences were reached in the second year of life. At this age less than 10% of West German children showed IgG antibodies to heat-labile enterotoxin. In Ecuador age-related ETEC-specific antibody titer increases correlated with age-related prevalence of diarrheal disease. On the other hand, pooled lipopolysaccharide from different ETEC-associated O serogroups could not be used as a seroepidemiologic marker of ETEC infections.

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