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. 2011 Nov;6(11):1861-4.
doi: 10.4161/psb.6.11.17761. Epub 2011 Nov 1.

Control of dicot leaf blade expansion by a WOX gene, STF

Million Tadege  1 , Hao Lin, Lifang Niu, Kirankumar S Mysore
Affiliations

Control of dicot leaf blade expansion by a WOX gene, STF

Million Tadege et al. Plant Signal Behav. 2011 Nov.

Abstract

WUSCHEL-RELATED HOMEOBOX (WOX) genes are plant specific transcription factors that serve as master switches controlling key developmental programs from embryo apical-basal asymmetric patterning to organizing stem cells and development of lateral organs. Recently, we reported the requirement of a WOX1/MAW-like gene, STENOFOLIA (STF), for blade outgrowth and leaf vascular patterning in Medicago truncatula and Nicotiana sylvestris. The stf mutant in Medicago produces narrow leaves where mediolateral outgrowth of the blade is severely curtailed while proximodistal growth and trifoliate identity remain unaffected. The lam1 mutant in N. sylvestris produces leaves devoid of blade tissue with just 1-2 layers of rudimentary strips and lacks stem elongation. stf and lam1 mutants have narrow petals and are female sterile due to defective ovule development. Morphological analysis of mutants and STF expression patterns suggest that STF regulates blade outgrowth mainly by controlling cell division in the margins of leaf primordium. Both the blade and flower phenotypes of lam1 can be complemented with WUS expressed under the STF promoter suggesting a conserved mechanism in stem cell maintenance and lateral organ development.

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Figures

Figure 1.
Figure 1.
Phylogenetic analysis of WUS, PRS and WOX1 like proteins within the modern clade of WOX class transcription factors. The phylogenetic tree was constructed using 72 amino acids around the homeodomain region and the MEGA4 software. Bootstrap values were generated from 1000 trials. Note that the WUS, PRS and STF/MAW like proteins from different species form three distinct subclades statistically well supported by bootstrap values. Both the WUS and PRS subclades are represented by members from dicots and monocots in which the monocot and dicot sequences of each subclade group separately within their respective subclade. Monocot sequences representing the STF/MAW subclade have not been identified in the sequenced genomes and extensive EST databases available to date.
See this image and copyright information in PMC

Comment on

  • Tadege M, Lin H, Bedair M, Berbel A, Wen J, Rojas CM, et al. STENOFOLIA regulates blade outgrowth and leaf vascular patterning in Medicago truncatula and Nicotiana sylvestris. Plant Cell. 2011;23:2125–42. doi: 10.1105/tpc.111.085340.

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