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Review
. 1990 Aug 20;152(34):2417-20.

[The hyper IgE syndrome. Job's syndrome]

[Article in Danish]
A M Drewes  1 , A T Olsson, A Andreasen
Affiliations
  • PMID: 2205959
Review

[The hyper IgE syndrome. Job's syndrome]

[Article in Danish]
A M Drewes et al. Ugeskr Laeger. .

Abstract

Since 1972, 150 cases of the hyper-IgE-syndrome have been reported. The clinical manifestations are rather homogeneous with recurrent subcutaneous infections and infections in the respiratory tract, mostly with juvenile onset. Laboratory tests show minor eosinophilia and elevated immunoglobulin E-levels are always seen, partly specific to Staphylococcus aureus. Also varying decreases of polymorphonuclear leucocyte-chemotactic response are seen. There is no specific treatment of the disorder, only treatment of current infections has proved valuable. A case history is presented.

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