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Review
. 2011 Nov;27(4):629-44.
doi: 10.1016/j.cger.2011.07.008.

The aging brain and neurodegenerative diseases

Affiliations
Review

The aging brain and neurodegenerative diseases

Gary W Duncan. Clin Geriatr Med. 2011 Nov.

Abstract

This article reviews the current thoughts on the effects of aging on the brain. Mechanisms of neurodegeneration are discussed, particularly those associated with Alzheimer's and Parkinson's diseases. Strategies of early detection of presymptomatic disease and potential future treatments are explored. Modification of risk factors and lifestyles for disease prevention is discussed.

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