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Review
. 1990:Suppl 1:63s-74s.
doi: 10.1051/rnd:19900706.

The role of chromosome abnormalities in reproductive failure

P A Jacobs  1
Affiliations
Free article
Review

The role of chromosome abnormalities in reproductive failure

P A Jacobs. Reprod Nutr Dev. 1990.
Free article

Abstract

The frequency of chromosome abnormalities in spontaneous abortions, stillbirths, livebirths and among all clinically recognized pregnancies is given. Data on the parental origin of sex chromosome abnormalities and certain autosomal trisomies determined using molecular probes are presented and the proportion of sperm and eggs that are nullisomic or disomic for a sex chromosome to an autosome 16, 18 or 21 is calculated.

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