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. 2012:803:265-71.
doi: 10.1007/978-1-61779-364-6_18.

Working with small molecules: preparing and storing stock solutions and determination of kinetic solubility

Andrea Wolf  1 , Satoko Shimamura, Friedrich B M Reinhard
Affiliations

Working with small molecules: preparing and storing stock solutions and determination of kinetic solubility

Andrea Wolf et al. Methods Mol Biol. 2012.

Abstract

The handling of organic compounds in the laboratory requires the use of organic (co-) solvents to mediate solubility. Advantages and disadvantages of the widely used solvent dimethylsulfoxide (DMSO) are discussed, and guidelines for dissolution and storage of compounds are given. Finally, nephelometry is introduced as a fast method to determine the kinetic solubility of a compound.

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