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Clinical Trial
. 1979 Mar 22;61(2):137-41.
doi: 10.1007/BF00426727.

Tardive dyskinesia: a clinical test of the supersensitivity hypothesis

M B Bowers Jr, D Moore, D Tarsy
Clinical Trial

Tardive dyskinesia: a clinical test of the supersensitivity hypothesis

M B Bowers Jr et al. Psychopharmacology (Berl). .

Abstract

Patients with tardive dyskinesia showed no significant difference in CSF HVA when compared with groups of schizophrenic or depressives. CSF cAMP in the tardive dyskinesia group was significantly lower when compared to schizophrenics but not depressives. These results do not support a dopamine-receptor supersensitivity hypothesis in permanent tardive dyskinesia.

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References

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