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Case Reports
. 2011 Jun;80 Suppl 1(Suppl 1):S31-5.
doi: 10.4174/jkss.2011.80.Suppl1.S31. Epub 2011 Jun 17.

Primary adenosquamous carcinoma of the colon

Dong Baek Kang  1 , Jung Taek Oh, Hyang Jeong Jo, Won Cheol Park
Affiliations
Case Reports

Primary adenosquamous carcinoma of the colon

Dong Baek Kang et al. J Korean Surg Soc. 2011 Jun.

Abstract

Adenosquamous cell carcinoma (Ad-SCC) of the colon is rare. The pathogenesis of Ad-SCC is unclear, however, several hypotheses have been suggested. The clinical presentation and gross findings of Ad-SCC of the colon are similar to those of adenocarcinoma of the colon, but Ad-SCC has a more aggressive clinical course and a poorer prognosis. We report on two cases of Ad-SCC of the colon with obstruction; a collision-type Ad-SCC that has not only obstruction but also numerous hepatic metastases, and a composite-type Ad-SCC treated with left hemicolectomy followed by an adjuvant chemotherapy.

Keywords: Adenosquamous cell carcinoma; Collision; Colon cancer; Composite.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
Abdominopelvic computed tomography shows obstructive enhancing mass on the sigmoid colon (arrow) with multiple hepatic metastatic masses on both lobes (arrowheads).
Fig. 2
Fig. 2
Macroscopic finding (left) shows the cut space of adenosquamous carcinoma of the sigmoid colon, and schematic diagram of the area (right) of the adenocarcinoma (gray area) and squamous cell carcinoma of sigmoid colon (black area).
Fig. 3
Fig. 3
Histopathological views reveal adenosquamous carcinoma of the sigmoid colon, showing the feature of collision between adenocarcinoma (a) and squamous cell carcinoma (s). (A) (H&E, ×40), and (B) (H&E, ×200).
Fig. 4
Fig. 4
Sigmoidoscopic finding shows circumferential obstructive mass at the sigmoid-descending junction.
Fig. 5
Fig. 5
Abdominopelvic computed tomography shows obstructive and circumferential enhancing wall mass at the sigmoid-descending junction (arrow) without distant metastasis.
Fig. 6
Fig. 6
Histopathological views reveal adenosquamous carcinoma of the sigmoid-descending junction, showing the composite feature between adenocarcinoma and squamous cell carcinoma. (A) H&E, ×40, (B) H&E, ×200.
See this image and copyright information in PMC

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