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Case Reports
. 2011 Aug;81(2):141-5.
doi: 10.4174/jkss.2011.81.2.141. Epub 2011 Aug 3.

Cystic lymphangioma of the pancreas

Bok-Kyung Sohn  1 , Chang-Ho Cho, Hyun-Dong Chae
Affiliations
Case Reports

Cystic lymphangioma of the pancreas

Bok-Kyung Sohn et al. J Korean Surg Soc. 2011 Aug.

Abstract

Lymphangioma is a benign form of neoplasm arising from the lymphatic system. It occurs as a result of congenital malformations of the lymphatics leading to the obstruction of local lymph flow and the development of lymphangiectasia. Lymphangiomas are common in pediatric patients, in the soft tissues of the neck and the axillae, but lymphangioma of the pancreas is extremely rare, accounting for less than 1% of these tumors. It occurs more frequently in females and is often located in the distal pancreas. Although extremely rare, cystic lymphangioma of the pancreas should be taken into consideration as a differential diagnosis of pancreatic cystic or retroperitoneal lesions, especially in women. Herein, we report on a case of cystic lymphangioma of the distal pancreas in a 37-year-old woman who was treated with complete surgical resection with a review of the literature.

Keywords: Cystic lymphangioma; Pancreas; Retroperitoneal space.

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Conflict of interest statement

No potential conflict of interest relevant to this article was reported.

Figures

Fig. 1
Fig. 1
Simple abdominal X-ray. Simple abdomen shows no bowel gas in the left upper quadrant with displacement of bowel to the right abdomen by the left upper quadrant mass.
Fig. 2
Fig. 2
Abdominal computed tomography (CT) scan. A contrast-enhanced helical CT scan of the abdomen at portal venous phase shows a huge, hypo-dense, well-capsulated and cystic lesion of unknown origin at the left upper quadrant of the abdomen (arrow).
Fig. 3
Fig. 3
Operative findings shows a huge, well-defined and cystic mass densely attached to the tail of the pancreas (arrow).
Fig. 4
Fig. 4
Gross finding of cystic lymphangioma of the pancreas. The surgical specimen is 15 × 10.5 × 7 cm in size, weighing 800 g with a multinodular external surface. The attached pancreas shows atrophy and inflammatory change. The spleen is unremarkable.
Fig. 5
Fig. 5
Microscopic findings. Variably sized multilocular cysts lined by thin attenuated endothelial cells and fibrotic stroma. Attached pancreas shows mild atrophy (H&E, ×40).
Fig. 6
Fig. 6
Immunohistochemical stain. The lining endothelial cells show strong immunopositivity for CD31 and D2-40 and weak positivity for CD34 (Immunohistochemistry, ×200).
See this image and copyright information in PMC

References

    1. Losanoff JE, Richman BW, El-Sherif A, Rider KD, Jones JW. Mesenteric cystic lymphangioma. J Am Coll Surg. 2003;196:598–603. - PubMed
    1. Leung TK, Lee CM, Shen LK, Chen YY. Differential diagnosis of cystic lymphangioma of the pancreas based on imaging features. J Formos Med Assoc. 2006;105:512–517. - PubMed
    1. Colovic RB, Grubor NM, Micev MT, Atkinson HD, Rankovic VI, Jagodic MM. Cystic lymphangioma of the pancreas. World J Gastroenterol. 2008;14:6873–6875. - PMC - PubMed
    1. Paal E, Thompson LD, Heffess CS. A clinicopathologic and immunohistochemical study of ten pancreatic lymphangiomas and a review of the literature. Cancer. 1998;82:2150–2158. - PubMed
    1. Schneider G, Seidel R, Altmeyer K, Remberger K, Pistorius G, Kramann B, et al. Lymphangioma of the pancreas and the duodenal wall: MR imaging findings. Eur Radiol. 2001;11:2232–2235. - PubMed

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