Comparative Study
doi: 10.1148/131.2.491.
Renal hyperconcentration of 99mTc-HEDP in experimental acute tubular necrosis
- PMID: 220670
- DOI: 10.1148/131.2.491
Item in Clipboard
Comparative Study
Renal hyperconcentration of 99mTc-HEDP in experimental acute tubular necrosis
Radiology.
1979 May.
Abstract
The effect of transient renal ischemia on renal concentration and distribution of 99mTc-HEDP, 99mTc-DMSA, and 99mTc-DTPA was compared in rabbits with acute tubular necrosis. Scintigrams were obtained after injection in normal rabbits or ones with unilateral or bilateral ischemia. 99mTc-HEDP concentration in ischemic tissue was 8 to 18 times normal 1--4 hours after injection, and the resulting images delineated the morphological changes in the ischemic kidneys more accurately than those obtained with DMSA or DTPA. Calcium concentration in the ischemic kidneys increased sixfold. 99mTc-HEDP may be useful in evaluation of renal failure secondary to tubular injury.
Similar articles
-
Evaluation of renal ischemia with 99mTc-pyrophosphate.Eur J Nucl Med. 1982;7(4):147-9. doi: 10.1007/BF00443919. Eur J Nucl Med. 1982. PMID: 6281016
-
Quantitation of ischemic injury with 99mTc-HEDP in experimental acute tubular necrosis.Invest Radiol. 1980 May-Jun;15(3):267-71. doi: 10.1097/00004424-198005000-00014. Invest Radiol. 1980. PMID: 6772593
-
Failure to visualize acutely injured kidneys with technetium-99m DMSA does not preclude recoverable function.J Nucl Med. 1986 Mar;27(3):377-9. J Nucl Med. 1986. PMID: 3012025
-
[Tubulointerstitial damage attributable to acute circulatory failure: postischemic acute renal failure].Nihon Rinsho. 1995 Aug;53(8):2027-33. Nihon Rinsho. 1995. PMID: 7563645 Review. Japanese.
-
B-mode sonography in acute renal failure.Nephron Clin Pract. 2006;103(2):c19-23. doi: 10.1159/000090604. Epub 2006 Mar 10. Nephron Clin Pract. 2006. PMID: 16543751 Review.
Cited by
-
Tc-99m Hydroxymethylene Diphosphonate (HMDP) Renal Uptake as a Surrogate Marker of Postoperative Impairment of the Glomerular Filtration Rate in Renal Tumor Patients Following Nephron-Sparing Surgery.Nucl Med Mol Imaging. 2014 Dec;48(4):262-71. doi: 10.1007/s13139-014-0284-2. Epub 2014 Jun 11. Nucl Med Mol Imaging. 2014. PMID: 26396630 Free PMC article.
-
Evaluation of renal ischemia with 99mTc-pyrophosphate.Eur J Nucl Med. 1982;7(4):147-9. doi: 10.1007/BF00443919. Eur J Nucl Med. 1982. PMID: 6281016
-
Evaluation of kidney grafts with 99mTc-methylene diphosphonate within 36 hours after transplantation: a marker of ischemic damage.Eur J Nucl Med. 1984;9(3):115-20. doi: 10.1007/BF00253512. Eur J Nucl Med. 1984. PMID: 6232139
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
