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Comment
. 2011;15(5):185.
doi: 10.1186/cc10346. Epub 2011 Oct 25.

Prognostic value of pulmonary dead space in patients with the acute respiratory distress syndrome

Affiliations
Comment

Prognostic value of pulmonary dead space in patients with the acute respiratory distress syndrome

Michael A Matthay et al. Crit Care. 2011.

Abstract

A study published in the previous issue of Critical Care demonstrates that measurement of the pulmonary dead-space fraction is superior to hypoxemia as an indicator of a favorable physiologic response to prone positioning in patients with severe acute respiratory distress syndrome. These results add to the growing evidence supporting the clinical and research value of measuring pulmonary dead space in patients with acute respiratory distress syndrome and using this pulmonary physiologic end-point as one indicator of a favorable response to therapy.

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References

    1. Charron C, Repesse X, Bouferrache K, Bodson L, Castro S, Page B, Jardin F, Vieillard-Baron A. PaCO2 and alveolar dead space are more relevant than PaO2/FiO2 in monitoring the respiratory response to prone position and acute inspiratory distress syndrome patients: a physiologic study. Crit Care. 2011;15:R175. doi: 10.1186/cc10324. - DOI - PMC - PubMed
    1. Siddiki H, Kojicic M, Li G, Yilmaz M, Thompson TB, Hubmayr RD, Gajic O. Bedside quantification of dead-space fraction using routine clinical data in patients with acute lung injury: secondary analysis of two prospective trials. Crit Care. 2010;14:R141. doi: 10.1186/cc9206. - DOI - PMC - PubMed
    1. Suter PM, Fairley HB, Isenberg MD. Optimum end-expiratory airway pressure in patients with acute pulmonary failure. N Engl J Med. 1975;292:284–289. doi: 10.1056/NEJM197502062920604. - DOI - PubMed
    1. Nuckton TJ, Alonso JA, Kallet RH, Daniel BM, Pittet JF, Eisner MD, Matthay MA. Pulmonary dead-space fraction as a risk factor for death in the acute respiratory distress syndrome. N Engl J Med. 2002;346:1281–1286. doi: 10.1056/NEJMoa012835. - DOI - PubMed
    1. Cepkova M, Kapur V, Ren X, Quinn T, Zhuo H, Foster E, Liu KD, Matthay MA. Pulmonary dead space fraction and pulmonary artery systolic pressure as early predictors of clinical outcome in acute lung injury. Chest. 2007;132:836–842. doi: 10.1378/chest.07-0409. - DOI - PubMed

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