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Case Reports
. 2011 Nov 9:11:142.
doi: 10.1186/1471-2377-11-142.

Acute infarct of the corpus callosum presenting as alien hand syndrome: evidence of diffusion weighted imaging and magnetic resonance angiography

Jun Liang Yuan  1 , Shuang Kun Wang, Xiao Juan Guo, Wen Li Hu
Affiliations
Case Reports

Acute infarct of the corpus callosum presenting as alien hand syndrome: evidence of diffusion weighted imaging and magnetic resonance angiography

Jun Liang Yuan et al. BMC Neurol. .

Abstract

Background: Infarcts of the corpus callosum are rare and have not been well documented previously. As for a variety of signs and symptoms presented, alien hand syndrome (AHS) can be easily overlooked.

Case presentation: In this report, we present a patient with a mixed types of AHS coexistence secondary to the corpus callosum infarction, including a motor type of AHS by intermanual conflict (callosal type AHS) and a sensory type of AHS by alien hand and left hemianesthesia (posterior AHS).

Conclusions: Our case may contribute to the early recognition of AHS and to explore the abnormal neural mechanism of AHS. To our knowledge, rare reports have ever documented such mixed AHS coexisting secondary to the callosal lesion, based on advanced neuroimaging methods as in our case.

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Figures

Figure 1
Figure 1
Multi-modal brain MRI. Axial T2-weighted (a) and FLAIR images (b) depicted T2 hyper-intensity and sagittal T1-weighted MRI (e) showed hypo-intensity in the genu, body and splenium of the corpus callosum. Axial DWI demonstrated high signal intensity in the observed T2 abnormality of the lesions of the corpus callosum (c). Corresponding ADC map illustrated matched abnormality, confirming restricted diffusion in the corpus callosum (d). MRA showed the absence of the A1 segment of the bilateral anterior cerebral artery. Atherosclerotic segment of stenosis in the area of the bilateral middle cerebral artery and left posterior cerebral artery were noted (arrows) (f).
Figure 2
Figure 2
Axial DWI showed high signal intensity in all the slices of the lesions of the corpus callosum.
See this image and copyright information in PMC

References

    1. Suwanwela NC, Leelacheavasit N. Isolated corpus callosal infarction secondary to pericallosal artery disease presenting as alien hand syndrome. J Neurol Neurosurg Psychiatry. 2002;72:533–536. - PMC - PubMed
    1. Doody RS, Jankovic J. The alien hand and related signs. J Neurol Neurosurg Psychiatry. 1992;55:806–810. doi: 10.1136/jnnp.55.9.806. - DOI - PMC - PubMed
    1. Kim YD, Lee ES, Lee KS, Kim JS. Callosal alien hand sign following a right parietal lobe infarction. J Clin Neurosci. 2010;17:796–797. doi: 10.1016/j.jocn.2009.10.018. - DOI - PubMed
    1. Yamaguchi S, Yamagata S, Bokura H, Toyoda G, Nagai A, Takahashi K, Kobayashi S. Somatosensory disinhibition and frontal alien hand signs following medial frontal damage. J Clin Neurosci. 2006;13:279–282. doi: 10.1016/j.jocn.2005.02.022. - DOI - PubMed
    1. Brion S, Jedynak CP. Disorders of interhemispheric transfer (callosal disonnection). 3 cases of tumor of the corpus callosum. The strange hand sign. Rev Neurol (Paris) 1972;126:257–266. - PubMed

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