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Editorial
. 2011 Nov 15;17(22):6955-7.
doi: 10.1158/1078-0432.CCR-11-2302. Epub 2011 Nov 8.

MAGE: the spell is broken

Katayoun Rezvani
Editorial

MAGE: the spell is broken

Katayoun Rezvani. Clin Cancer Res. .

Abstract

The success of immunotherapy in Hodgkin lymphoma is hampered partly by limited expression of tumor-specific antigens in the malignant cells. One strategy to increase tumor immunogenicity may be to enhance the expression of Hodgkin lymphoma-specific antigens such as MAGE-A4 using epigenetic-modifying drugs in combination with cancer testis antigen-specific immunotherapy.

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