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. 2011 Nov 9;2011(11):CD005531.
doi: 10.1002/14651858.CD005531.pub4.

Chinese medicinal herbs for measles

Shou Chen  1 , Taixiang Wu, Xiangyu Kong, Hao Yuan
Affiliations

Chinese medicinal herbs for measles

Shou Chen et al. Cochrane Database Syst Rev. .

Abstract

Background: Measles is an infectious disease caused by the Morbillivirus. Chinese physicians believe that medicinal herbs are effective in alleviating symptoms and preventing complications. Chinese herbal medicines are dispensed according to the particular symptoms. This is the second update of a Cochrane Review first published in 2006.

Objectives: To assess the effectiveness and possible adverse effects of Chinese medicinal herbs for measles.

Search methods: We searched the Cochrane Central Register of Controlled Clinical Trials (CENTRAL Issue 1, 2011) which contains the Cochrane Acute Respiratory Infections Group's Specialised Register, MEDLINE (1966 to March week 5, 2011), EMBASE (1980 to April 2011), Web of Science (2005 to 30 April 2011), AMED (1985 to 30 April 2011), Chinese Biomedical Database (1976 to 30 June 2011), VIP Information (1989 to 30 June 2011), China National Knowledge Infrastructure (CNKI) (1976 to 30 June 2011), Chinese Journals full-article database (1994 to 30 June 2011) and the metaRegister of Controlled Trials for ongoing trials.

Selection criteria: Randomised controlled trials (RCTs) of Chinese medicinal herbs in patients with measles (without complications).

Data collection and analysis: Two review authors (SC, TW) independently assessed trial quality and extracted data. We telephone interviewed the trial authors for missing information regarding participant allocation. Some trials allocated participants according to the sequence they were admitted to the trials, that is to say, by using a pseudo-random allocation method. None of the trials concealed the allocation or used blinding methods.

Main results: We did not identify any suitable trials for inclusion. In this updated review we identified 80 trials which claimed to use random allocation. We contacted 32 trial authors by telephone and learned that the allocation methods used were not randomised. We excluded 34 studies because the participants experienced complications such as pneumonia. We excluded 10 trials because of non-random allocation and complications experienced by the participants. We were unable to contact the remaining four trials' authors, so they require further assessment and have been allocated to the 'Studies awaiting classification' section.

Authors' conclusions: There is no RCT evidence for or against Chinese medicinal herbs as a treatment for measles. We hope high-quality, robust RCTs in this field will be conducted in the future.

PubMed Disclaimer

Conflict of interest statement

None known.

Figures

1
1
Study flow diagram.
See this image and copyright information in PMC

Update of

References

References to studies excluded from this review

Ai 2004 {published data only}
    1. Ai ZH, Zhong WC. Observation for curative effect of Qingkailing injection in the treatment of 24 children with measles complicated pneumonia. Journal of Beijing University of Traditional Chinese Medicine 2004;11(1):30.
Bo 2010 {published data only}
    1. Bo SL. Observation for the clinical effect of integrated traditional Chinese and Western medicine in the treatment of 46 children with measles complicated with pneumonia. China Practical Medicine 2010;5(25):190‐1.
Cai 2004 {published data only}
    1. Cai JH, Li CX, Xue BM, Luo ZX. Brushing and bathing by using Chinese herbal medicine lotion for treating and nursing adult with measles. Journal of Guangdong Medical College 2004;22(5):548‐9.
Chen 2010 {published data only}
    1. Chen JJ. Clinical observation of integrative medicine in the treatment of atypical measles. Chinese Community Doctors 2010;12(249):136.
Cheng 2002 {published data only}
    1. Cheng LS. Observation for effect of Chinese herbal medicine in the treatment of children with measles. Journal of Nursing Science 2002;17(9):673‐4.
Chu 2011 {published data only}
    1. Che ZY, Li HY, Li MY. The effect of Tanreqing injection in the treatment of 136 patients with measles. National Medical Frontiers of China 2011;6(1):36, 63.
Cui 1999 {published data only}
    1. Cui JH. Observation for curative effect of Eshuyou in the treatment of 35 patients with measles. Journal of Linyi Medical College 1999;21(2):115‐6.
Cui 2006 {published data only}
    1. Cui QH, He KR. A clinical efficacy analysis for Tanreqing injection in the treatment of children suffering measles with pneumonia. Chinese Journal for Practical Rural Doctors 2006;13(2):40‐1.
Ding 2008 {published data only}
    1. Ding J, Tian WG. Clinical study of Tanreqing injection for measles. Modern Medicine & Health 2008;24(5):656‐7.
Dong 2005 {published data only}
    1. Dong ZQ. Observation for Astragalus injection in the treatment of 50 children suffering measles combined with pneumonia. Henan Traditional Chinese Medicine 2005;25(8):73‐4.
Dong 2011 {published data only}
    1. Dong HJ, Mi YQ. The effect of xuebijin injection in the treatment of 81 children suffering measles complicated with heart failure and pneumonia. Shanxi Journal of Traditional Chinese Medicine 2011;32(3):293‐4.
Du 2008 {published data only}
    1. Du J, Hu GB, Li XQ. Observation for integrative traditional Chinese medicine and Western medicine in the treatment of 85 children with measles. Zhejiang Journal of Traditional Chinese Medicine 2008;43(12):709.
Fan 2006 {published data only}
    1. Fan HY, Xie WW. Observation for integrative therapy of traditional Chinese Medicine and Western medicine in the treatment of atypical measles. Shanxi Journal of Traditional Chinese Medicine 2006;22(4):36‐7.
Fan 2006b {published data only}
    1. Fan YF. Observation for Tanreqing injection in the treatment of 30 patients with measles. Journal of Emergency in Traditional Chinese Medicine 2006;15(5):489.
Fang 2010 {published data only}
    1. Fang P, Lian FL. The clinical report of yanhuning injection in the treatment of 126 children with measles. Journal of Clinical and Experiment Medicine 2010;9(24):1886‐7.
Gu 2005 {published data only}
    1. Gu HH, Chen QW, Xue LY. Observation for astragalus in the treatment of 264 cases suffering measles with myocardial damage. Zhejiang Clinical Medical Journal 2005;7(8):860‐1.
Guan 2009 {published data only}
    1. Guan CY. The effect of Tanreqing injection in the treatment of 35 infant suffering measles with pneumonia. Journal of Emergency Traditional Chinese Medicine 2009;18(5):786,789.
Gui 2008 {published data only}
    1. Gui XH. Observation for Tanreqing injection in the treatment of measles with acute tracheal bronchitis. Public Medical Forum Journal 2008;12(5):173‐4.
Guo 2008 {published data only}
    1. Guo ZH, Li L. Observation for Asarone plus penicillin injection in the treatment of children suffering measles with pneumonia. Chinese Journal of Clinical Medicine Research 2008;19:22‐3.
Guo 2010 {published data only}
    1. Guo ZJ, Li L. A clinical effect of asarone injection combined with penicillin in the treatment of children suffering measles complicated with pneumonia. Chinese Journal of Modern Drug Application 2010;4(13):121‐2.
Han 2006a {published data only}
    1. Han ZQ, Zhu ZH, Liu XZ. A clinical observation for Tanreqing in the treatment of 58 children with measles. Modern Journal of Integrated Traditional Chinese and Western Medicine 2006;15(13):1786.
Han 2006b {published data only}
    1. Han ZQ, Liu XZ, Hou LP. Clinical observation for Tanreqing injection in treatment of 32 children suffering measles with pneumonia. China Medicine Hygiene 2006;6(17):52‐3.
Hu 2006 {published data only}
    1. Hu CR, Zhu C. A clinical observation for Tanreqing injection in the treatment of measles with pneumonia. Chinese Contemporary Medical Science 2006;16:102.
Ji 2008 {published data only}
    1. Ji XL. Observation for curative effect of modified herbal decoction plus to Western medicine in the treatment of adults with measles. Shanxi Journal of Traditional Chinese Medicine 2008;24(18):19‐20.
Li 1999 {published data only}
    1. Li B, Gu SX, Ma SQ. Observation for curative effect of Qingkailing injection in the treatment of 60 cases with measles complicated with pneumonia. Ningxia Medical Journal 1999;21(12):745.
Li 2000 {published data only}
    1. Li GF. Observation for curative effects of integrated traditional Chinese and Western medicine 60 children with severe measles. Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2000;7(5):310‐1.
Li 2002 {published data only}
    1. Li YS, Liu CY, Pan L. Observation curative effect for Danshen compound injection in the treatment children suffering measles complicated with pneumonia. Chinese Journal of Integrated Traditional and Western Medicine 2002;22(4):311.
Li 2003 {published data only}
    1. Li LY. Observation curative effect for integrated traditional Chinese and Western medicine in the treatment of 59 cases suffering measles complicated with encephalitis. Chinese Journal of Information on Traditional Chinese Medicine 2003;10(10):70‐1.
Li 2005 {published data only}
    1. Li HZ. Observation for efficacy of Tanreqing in the treatment of measles combined with bronchial pneumonia. Central Plains Medical Journal 2005;32(20):65.
Li 2008 {published data only}
    1. Ye Li, Liu ZM, Chen W. An observation for efficacy of Tanreqing injection in the treatment of measles combined with bronchial pneumonia. Journal of Emergency in Traditional Chinese Medicine 2008;17(2):157‐67.
Li 2009 {published data only}
    1. Li Q, Zhang M, Du DY, Jiang LP. Observation for the clinical effect of integrated traditional Chinese and Western medicine in the treatment of 20 cases of measles complicate pneumonia. Zhejiang Journal of Traditional Chinese Medicine 2009;44(3):174‐5.
Liang 2007 {published data only}
    1. Liang C. A clinical observation for tanreqing in treatment of 30 patients suffering measles complicated with bronchial pneumonia. Medical Academic Forum 2007;1:86.
Liao 2011 {published data only}
    1. Liao HB, Li XZ. The clinical effect of redunin injection in the treatment of measles. Medicine Information 2011;24(3):1360.
Liu 2000b {published data only}
    1. Liu H, Wei RH. Qingrexuanfei for children suffering measles complicated with bronchial pneumonia. Journal of Tianjin College of Traditional Chinese Medicine 2000;19(4):17.
Liu 2005 {published data only}
    1. Liu HJ. A clinical observation for tanreqing injection for 50 children suffering measles combined with pneumonia. Central Plains Medical Journal 2005;32(23):80.
Liu 2007 {published data only}
    1. Liu B, Zhao H. Tanreqing injection in the treatment of 36 patients with measles. China Naturopathy 2007;15(11):41‐2.
Liu 2009 {published data only}
    1. Liu XS, Luo RX. Observation for clinical effect of integrated traditional Chinese and Western medicine in the treatment of 50 children suffering measles complicated with pneumonia. Journal of Practical Traditional Chinese Medicine 2009;25(8):547.
Liu 2010 {published data only}
    1. Liu GJ, Wang HQ, Zhang JL. The effect of tanreqing injection in the treatment of 52 children suffering measles complicated with pneumonia. Clinical Medicine 2010;30(4):112.
Lou 2010 {published data only}
    1. Lou HS, Liu WJ, Li JH. Clinical observation for effect of compound glycyrrhizin injection combined with ribavirin in the treatment of measles. Journal of Medical Forum 2010;31(22):185.
Lu 2008 {published data only}
    1. Nan Lu. Observation for chuanhuning in the treatment of 23 adults with measles. Modern Journal of Integrated Traditional Chinese and Western Medicine 2008;17(15):2331‐2.
Luo 2009 {published data only}
    1. Luo HX. Observation for clinical effect of integrated traditional Chinese and Western medicine in the treatment of 30 patients with measles. Chinese Journal of Traditional Medical Science and Technology 2009;16(2):154‐5.
Ma 2009 {published data only}
    1. Ma MJ, Li XM. The effect of qinretouzhen decoction in the treatment of 83 children suffering measles complicated with pneumonia. Shandong Journal of Traditional Chinese Medicine 2009;28(8):534‐5.
Ma 2009a {published data only}
    1. Ma XH. Observation for clinical effect of yanhuning injection in the treatment of 60 children suffering measles complicated with pneumonia. Modern Chinese Health 2009;25(12):1821.
Mei 2002 {published data only}
    1. Mei M. Observation for curative effect of qingkailing plus ribavirin in the treatment of measles. Journal of Bengbu Medical College 2002;27(4):346.
Niu 2005 {published data only}
    1. Niu LX, Du AM, Liu XL, Shi YY, Liu SZ, Liu CK. Observation for Tanreqing in the treatment of measles with bronchial pneumonia. Clinical Medicine 2005;25(11):86.
Niu 2006 {published data only}
    1. Niu XL, Dang ZQ, Zhao CP. Xuanfei touzhen detoxification in treatment of 50 patients with severe measles. Shaanxi Journal of Traditional Chinese Medicine 2006;26(9):1081‐2.
Nu 2010 {published data only}
    1. Nu ET, Rena AEK, Huang C, Bao B, Xu JP, Li G. Observation for the therapeutic effect of tanreqing plus interferon α‐1b in the treatment of measles. Acta Academiae Medicinae 2010;11(12):965‐6.
Pan 2005 {published data only}
    1. Pan CX, Li MH, Hu CX. Adjunctive danshen compound injection for severe infant pneumonia after measles. Journal of Handan Medical College 2005;18(1):29.
Pei 2004 {published data only}
    1. Pei L, Liu S. Clinical observations for Yujin injection in the treatment of children suffering measles combined with pneumonia. Journal of Occupational Health and Damage 2004;19(1):40.
Qian 2003 {published data only}
    1. Qian YP. Observation for integrated traditional Chinese and Western medicine in the treatment of 52 children suffering measles complicated with pneumonia. Henan Traditional Chinese Medicine 2003;23(2):41‐2.
Sun 2009 {published data only}
    1. Sun LL Qian XF. Clinical observation for coriander decoction in the treatment of measles. Chinese Journal of Misdiagnostics 2009;9(32):7854‐5.
Tan 2001 {published data only}
    1. Tan XP. Fudichouxin in the treatment of 34 children suffering measles complicated with pneumonia. Journal of Sichuan Chinese Medicine 2001;19(2):50‐1.
Wang 1994 {published data only}
    1. Wang EY. Integrated traditional Chinese and Western medicine in the treatment of 188 cases of measles complicated with pneumonia. Chinese Journal of Integrated Traditional Chinese and Western Medicine 1994;14(4):236.
Wang 1995a {published data only}
    1. Wang CY. Clinical observations for integrated traditional Chinese and Western medicine in the treatment of measles complicated with pneumonia. Modern Journal of Integrated Traditional Chinese and Western Medicine 1995;4(2):91.
Wang 1995b {published data only}
    1. Wang DY. Integrated traditional Chinese and Western medicine in the treatment of 82 cases of severe measles. Journal of Sichuan Chinese Medicine 1995;10:42.
Wang 1996 {published data only}
    1. Wang ZK, Tang CL. Observation for curative effect of qingkailing injection in the treatment of measles. Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 1996;3(10):471‐2.
Wang 1997 {published data only}
    1. Wang XD, Ma H, Kong FX. Observation for curative effect of Shuanghuanglian powder injection in the treatment of 42 children suffering measles complicated with pneumonia. Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 1997;4(10):449‐50.
Wang 2008a {published data only}
    1. Wang X. A clinical observation for maxing shigan decoction in the treatment of measles combined with pneumonia. Journal of Clinical and Experimental Medicine 2008;7(9):153.
Wang 2008b {published data only}
    1. Wang PS, Song DM, Wang Y, Jing JH, Gao H. A clinical observation for Xiyanping in the treatment of 50 adult with measles. China Practical Medical 2008;3(36):150‐1.
Wu 2004 {published data only}
    1. Wu YL. Clinical observation for shuanghuanlian in the treatment of adult with measles. Modern Medicine and Health 2004;20(2):113.
Xia 2011 {published data only}
    1. Xia YY. The effect of yanhuning injection combined with ribavirin on the treatment of measles. Medicine Information 2011;24(4):1997‐8.
Xu 2005 {published data only}
    1. Xu YY. Observation for Tanreqing injection in the treatment of 48 cases of measles. Journal of Emergency in Traditional Chinese Medicine 2005;14(11):1064.
Xue 2006 {published data only}
    1. Xue CQ, Wang ZQ. Tanreqing injection in the treatment of 62 patients with measles. Shanxi Journal of Traditional Chinese Medicine 2006;27(3):276.
Yan 2009 {published data only}
    1. Yan ZX, Zhang BP, Zhao Y. Observation for the effect of tanreqing injection combined with sou medrol in the treatment of children with measles complicated with pneumonia. Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease 2009;17(3):188‐9.
Yang 2006a {published data only}
    1. Yang JZ, Han FQ, Zhang YH. Tanreqing in the treatment of measles combined with pneumonia. Journal of Medical Forum 2006;27(17):93.
Yang 2006b {published data only}
    1. Yang RL, Ma JP, Ma HD. A clinical observation for xiyanping injection in the treatment of 61 children with measles complicated with pneumonia. Journal of Military Surgeon in Southwest China 2006;8(5):51‐2.
Yang 2008 {published data only}
    1. Yang J, Wei M. A clinical observation for tanreqing injection in the treatment of measles. Medical Journal of National Defending Forces in Southwest China 2008;18(5):693‐4.
Zhang 2004 {published data only}
    1. Zhang XZ, Zhang CP, Xia XS. Clinical observations for qingfeijiedu decoction in the treatment of 86 patients with measles. Journal of Xinxiang Medical College 2004;21(5):428‐9.
Zhang 2006a {published data only}
    1. Zhang F, Jiang FX. A clinical observation for tanreqing in the treatment of 32 patients with measles complicated with pneumonia. Journal of Medical Theory and Practice 2006;19(5):551.
Zhang 2006b {published data only}
    1. Zhang YB, Liu ZY, Liang CQ, Zhao F, Fu YM, Yang XY, et al. Tanreqing injection in the treatment of adult measles and immune regulation. Journal of Emergency in Traditional Chinese Medicine 2006;15(11):1231‐2.
Zhang 2008 {published data only}
    1. Zhang BP, Zhao Y. Tanreqing injection in the treatment of 49 children with measles combined with pneumonia. Journal of Practical Medicine 2008;24(14):2517.
Zhang 2009 {published data only}
    1. Zhang SJ, Wang CF, Qi YY, Chen JJ. Clinical observation for Qinzhen decoction in the treatment of 32 patients with measles. Chinese Journal of Integrative Medicine 2009;15(5):389‐92. - PubMed
Zhang 2010 {published data only}
    1. Zhang ZH, Wei ZY, Wang L. The effect of Tanreqing injection in the treatment of children with measles complicated with pneumonia. Chinese Jounral of Clinical Rational Drug Use 2010;3(8):58‐9.
Zhao 2002 {published data only}
    1. Zhao GR, Lin QR, Zhuo ZQ. Observation for curative effect of eshuyou putaotang injection in the treatment of children with measles complicated with bronchial pneumonia. Journal of Medical Theory and Practice 2002;15(7):815.
Zhao 2005 {published data only}
    1. Zhao QB, Wang YC. Traditional Chinese and Western medicine in the treatment of 70 patients with measles complicated with bronchial pneumonia. Journal of Practical Traditional Chinese Internal Medicine 2005;19(6):531.
Zheng 2003 {published data only}
    1. Zheng XM. Observation for effect of xingnaojing in the treatment of measles fever. Zhejiang Journal of Integrated Traditional Chinese and Western Medicine 2003;13(4):256.
Zhou 2006 {published data only}
    1. Zhou J, Li DC, Fan HS, Shen LH. Observation for tanreqing injection in the treatment of measles complicated with pneumonia. Journal of Emergency in Traditional Chinese Medicine 2006;18(8):837‐46.
Zhou 2009 {published data only}
    1. Zhou L. Observation for the clinical effect of integrated traditional Chinese and Western medicine in the treatment of 42 patients with measles. Chinese Journal of Modern Drug Application 2009;3(9):120‐1.
Zhou 2010 {published data only}
    1. Zhou YN, Mao HM. Observation for the effect of yanhuning injection in the treatment of measles. Chinese Journal of Rural Medicine and Pharmacy 2010;44:67.
Zhu 1994 {published data only}
    1. Zhu CM, Chen SY. Observation for curative effect of shuanghuanglian powder in the treatment of children with measles. Journal of Emergency in Traditional Chinese Medicine 1994;3(5):240.

References to studies awaiting assessment

Cui 1994 {published data only}
    1. Cui W. Niuxigancao decoction in the treatment of 30 children with measles complicated with laryngitis. Shanxi Journal of Traditional Chinese Medicine 1994;15(8):345.
Feng 1994 {published data only}
    1. Feng ZY, Huang LQ. Observation for curative effect of shuanghuanglian injection in the treatment of 105 children with measles. Central China Medical Journal 1994;18(1):15.
Jiao 2001 {published data only}
    1. Jiao JP. Analysis for effect of Eshuyou injection in the treatment of 40 patients with measles. Shandong Medical Journal 2001;41(17):72‐3.
Liu 1996 {published data only}
    1. Liu Q. Integrated traditional Chinese and Western medicine for children with measles. Journal of Sichuan Traditional Chinese Medicine 1998;14(12):42.

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