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Comment
. 2011 Nov 15;21(5):808-10.
doi: 10.1016/j.devcel.2011.10.021.

Autophagic factors cut to the bone

Amir Gelman  1 , Zvulun Elazar
Affiliations
Free article
Comment

Autophagic factors cut to the bone

Amir Gelman et al. Dev Cell. .
Free article

Abstract

Autophagy is an intracellular membrane-trafficking pathway for the delivery of proteins and organelles to lysosomes for degradation and recycling. DeSelm and coworkers (2011) now describe an essential role for autophagic proteins in the trafficking and fusion of lysosomes at the site of bone resorption: the osteoclast ruffled border.

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