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. 2011 Nov 1;2(11):3047-57.
doi: 10.1364/BOE.2.003047. Epub 2011 Oct 6.

Tissue oximetry: a comparison of mean values of regional tissue saturation, reproducibility and dynamic range of four NIRS-instruments on the human forearm

Simon Hyttel-Sorensen, Line C Sorensen, Joan Riera, Gorm Greisen

Tissue oximetry: a comparison of mean values of regional tissue saturation, reproducibility and dynamic range of four NIRS-instruments on the human forearm

Simon Hyttel-Sorensen et al. Biomed Opt Express. .

Abstract

We compared absolute values of regional tissue hemoglobin saturation (StO(2)), reproducibility, and dynamic range of four different instruments on the forearm of adults. The sensors were repositioned 10 times on each subject. Dynamic range was estimated by exercise with subsequent arterial occlusion. Mean StO(2) was 70.1% ± 6.7 with INVOS 5100, 69.4% ± 5.0 with NIRO 200 NX, 63.4% ± 4.5 with NIRO 300, and 60.8% ± 3.6 with OxyPrem. The corresponding reproducibility S(w) was 5.4% (CI 4.4-6.9), 4.4% (CI 3.5-5.2), 4.1% (CI 3.3-4.9), and 2.7% (CI 2.2-3.2), respectively. The dynamic ranges ΔStO(2) were 45.0%, 46.8%, 44.8%, and 27.8%, respectively. In conclusion, the three commercial NIRS instruments showed different absolute values, whereas reproducibility and dynamic range were quite similar.

Keywords: (170.1470) Blood or tissue constituent monitoring; (300.6190) Spectrometers.

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Figures

Fig. 1
Fig. 1
Illustration of sensor positions during resitings (translucent white rectangle) and dynamic measurements (four opaque white ovals with position number). S, source. D, detector.
Fig. 2
Fig. 2
For each instrument: On the left side the mean StO2 with 95% CI (box) and 95% reference range. On the right side dynamic range with mean StO2 pre- and post-exercise with 95% CI (boxes)
Fig. 3
Fig. 3
A tracing of StO2 with the NIRO 200 NX during exercise and arterial occlusion
See this image and copyright information in PMC

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