Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2012 Feb;38(2):121-6.
doi: 10.1136/medethics-2011-100096. Epub 2011 Nov 11.

How to write a systematic review of reasons

Affiliations

How to write a systematic review of reasons

Daniel Strech et al. J Med Ethics. 2012 Feb.

Abstract

Systematic reviews, which were developed to improve policy-making and clinical decision-making, answer an empirical question based on a minimally biased appraisal of all the relevant empirical studies. A model is presented here for writing systematic reviews of argument-based literature: literature that uses arguments to address conceptual questions, such as whether abortion is morally permissible or whether research participants should be legally entitled to compensation for sustaining research-related injury. Such reviews aim to improve ethically relevant decisions in healthcare, research or policy. They are better tools than informal reviews or samples of literature with respect to the identification of the reasons relevant to a conceptual question, and they enable the setting of agendas for conceptual and empirical research necessary for sound policy-making. This model comprises prescriptions for writing the systematic review's review question and eligibility criteria, the identification of the relevant literature, the type of data to extract on reasons and publications, and the derivation and presentation of results. This paper explains how to adapt the model to the review question, literature reviewed and intended readers, who may be decision-makers or academics. Obstacles to the model's application are described and addressed, and limitations of the model are identified.

PubMed Disclaimer

Conflict of interest statement

Competing interests: NS is collaborating with the UK's National Research Ethics Service (NRES) to write NRES's first guidance on post-trial access.

References

    1. Eden J, Levit L, Berg A, et al. Finding What Works in Health Care: Standards for Systematic Reviews.Institute of Medicine (IOM) Committee on Standards for Systematic Reviews of Comparative Effectiveness Research Washington, DC: National Academies Press, 2011 - PubMed
    1. Moher D, Liberati A, Tetzlaff J, et al. Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. Ann Intern Med 2009;151:264–9; W64. - PubMed
    1. Dixon-Woods M, Agarwal S, Jones D, et al. Synthesising qualitative and quantitative evidence: a review of possible methods. J Health Serv Res Policy 2005;10:45–53 - PubMed
    1. Pope C, Mays N, Popay J. Informing policy making and management in healthcare: the place for synthesis. Healthcare Policy 2006;1:43–8 - PMC - PubMed
    1. Strech D, Persad G, Marckmann G, et al. Are physicians willing to ration health care? Conflicting findings in a systematic review of survey research. Health Policy 2009;90:113–24 - PMC - PubMed

Publication types