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Review
. 2012 May;26(5):1201-4.
doi: 10.1007/s00464-011-2037-y. Epub 2011 Nov 15.

A review of the role of GERD-induced aspiration after lung transplantation

P Marco Fisichella  1 , Christopher S Davis, Elizabeth J Kovacs
Affiliations
Review

A review of the role of GERD-induced aspiration after lung transplantation

P Marco Fisichella et al. Surg Endosc. 2012 May.

Abstract

The increased prevalence of gastroesophageal reflux disease (GERD) in lung transplantation patients has been established; however, many questions persist regarding the relationship of GERD to aspiration and its potential to induce pulmonary allograft failure. Moreover, the biological implications of aspiration in lung transplantation have yet to be fully elucidated. The goal of this review was to assess the relationship between GERD and aspiration, focusing on the role of these events in the development of allograft injury after lung transplantation.

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Conflict of interest statement

Disclosure Drs. Fisichella, Davis, and Kovacs have no conflicts of interest or financial ties to disclose.

References

    1. Trulock EP, Christie JD, Edwards LB, Boucek MM, Aurora P, Taylor DO, Dobbels F, Rahmel AO, Keck BM, Hertz MI. Registry of the International Society for Heart, Lung Transplantation: twenty-fourth official adult lung, heart-lung transplantation report–2007. J Heart Lung Transpl. 2007;26(8):782–795. - PubMed
    1. Estenne M, Hertz MI. Bronchiolitis obliterans after human lung transplantation. Am J Respir Crit Care Med. 2002;166:440–444. - PubMed
    1. Hartwig MG, Appel JZ, Li B, Hsieh CC, Yoon YH, Lin SS, Irish W, Parker W, Davis RD. Chronic aspiration of gastric fluid accelerates pulmonary allograft dysfunction in a rat model of lung transplantation. J Thorac Cardiovasc Surg. 2006;131(1):209–217. - PubMed
    1. Lau CL, Palmer SM, Howell DN, McMahon R, Hadjiliadis D, Gaca J, Pappas TN, Davis RD, Eubanks S. Laparoscopic antireflux surgery in the lung transplant population. Surg Endosc. 2002;16(12):1674–1678. - PubMed
    1. Hadjiliadis D, Duane Davis R, Steele MP, Messier RH, Lau CL, Eubanks SS, Palmer SM. Gastroesophageal reflux disease in lung transplant recipients. Clin Transpl. 2003;17(4):363–368. - PubMed

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