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. 2011 Nov 9:4:41.
doi: 10.3389/fnmol.2011.00041. eCollection 2011.

The circadian clock, reward, and memory

Affiliations

The circadian clock, reward, and memory

Urs Albrecht. Front Mol Neurosci. .

Abstract

During our daily activities, we experience variations in our cognitive performance, which is often accompanied by cravings for small rewards, such as consuming coffee or chocolate. This indicates that the time of day, cognitive performance, and reward may be related to one another. This review will summarize data that describe the influence of the circadian clock on addiction and mood-related behavior and put the data into perspective in relation to memory processes.

Keywords: addiction; cell death; circadian rhythms; cortisol; neurogenesis; synaptic plasticity.

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Figures

Figure 1
Figure 1
Schematic diagramm of the potential integration of memory, reward, and circadian clock information. Signaling pathways affecting the learning/memory, reward, and circadian clock systems are depicted.

References

    1. Abarca C., Albrecht U., Spanagel R. (2002). Cocaine sensitization and reward are under the influence of circadian genes and rhythm. Proc. Natl. Acad. Sci. U.S.A. 99, 9026–9030 10.1073/pnas.142039099 - DOI - PMC - PubMed
    1. Albrecht U., Sun Z. S., Eichele G., Lee C. C. (1997). A differential response of two putative mammalian circadian regulators, mper1 and mper2, to light. Cell 91, 1055–1064 10.1016/S0092-8674(00)80495-X - DOI - PubMed
    1. Albrecht U., Zheng B., Larkin D., Sun Z. S., Lee C. C. (2001). MPer1 and mper2 are essential for normal resetting of the circadian clock. J. Biol. Rhythms 16, 100–104 10.1177/074873001129001791 - DOI - PubMed
    1. Andretic R., Chaney S., Hirsh J. (1999). Requirement of circadian genes for cocaine sensitization in Drosophila. Science 285, 1066–1068 10.1126/science.285.5430.1066 - DOI - PubMed
    1. Anisman H., Merali Z., Poulter M. O., Hayley S. (2005). Cytokines as a precipitant of depressive illness: animal and human studies. Curr. Pharm. Des. 11, 963–972 10.2174/1381612053381701 - DOI - PubMed

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