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. 2011:2011:981497.
doi: 10.1155/2011/981497. Epub 2011 Apr 14.

Treatment of Deep Vein Thrombosis with Continuous IV Infusion of LMWH: A Retrospective Study in 32 Children

Veronika Fiamoli  1 , Jan Blatny, Ondrej Zapletal, Svetlana Kohlerova, Eva Janousova
Affiliations

Treatment of Deep Vein Thrombosis with Continuous IV Infusion of LMWH: A Retrospective Study in 32 Children

Veronika Fiamoli et al. Thrombosis. 2011.

Abstract

Thirty-two consecutive children aged 0-18 years with VTE treated with LMWH administered as a continuous infusion (CI) were identified at the Children's University Hospital Brno. The treatment led to at least partial resolution of the thrombus within two weeks in 85% of patients. There were no adverse events or increased bleeding reported in any patients. No recurrences were observed during a followup period of 6 months. Although continuous infusion should not replace subcutaneous (SC) administration of LMWH, CI appeared to be safe and efficient and may provide an alternate method of administering LMWH in a subset of the paediatric population where SC administration may not be feasible. Further prospective studies are needed to support the promising findings of our pilot clinical observation.

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Figures

Figure 1
Figure 1
Number of patients according to age.
Figure 2
Figure 2
Thrombus resolution.
See this image and copyright information in PMC

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