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Case Reports
. 2011 Sep;5(3):528-33.
doi: 10.1159/000331799. Epub 2011 Sep 10.

Autoimmune pancreatitis exhibiting multiple mass lesions

Masahiro Shiokawa  1 , Yuzo Kodama, Yukiko Hiramatsu, Akira Kurita, Yugo Sawai, Norimitsu Uza, Tomohiro Watanabe, Tsutomu Chiba
Affiliations
Case Reports

Autoimmune pancreatitis exhibiting multiple mass lesions

Masahiro Shiokawa et al. Case Rep Gastroenterol. 2011 Sep.

Abstract

Our case is a first report of autoimmune pancreatitis with multiple masses within the pancreas which was pathologically diagnosed by endoscopic ultrasound-guided fine needle aspiration and treated by steroid. The masses disappeared by steroid therapy. Our case is informative to know that autoimmune pancreatitis sometimes exhibits multiple masses within the pancreas and to diagnose it without unnecessary surgery.

Keywords: Autoimmune pancreatitis; Endoscopic ultrasound-guided fine needle aspiration; IgG4; Mass forming; Pancreatic cancer.

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Figures

Fig. 1
Fig. 1
CT revealed mass lesions in the head (a) and body (b) of the pancreas (arrows); early phase. They showed slight delayed enhancement during the late phase (arrows in c, d).
Fig. 2
Fig. 2
Cell block in the two nodules showed dense lymphoplasmacytic infiltrate and significant replacement of pancreatic parenchyma by irregular fibrosis (H&E, ×400) (a). Numerous plasma cells in the two nodules showed positive immunoreactivity for IgG4 (H&E, ×400) (b). Cell block in the normal pancreas showed almost normal acinar cells, no lymphoplasmacytic infiltrate and no fibrosis (H&E, ×400) (c).
Fig. 3
Fig. 3
The two nodules in the head (a) and body (b) had disappeared on CT.
See this image and copyright information in PMC

References

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