Occult hepatitis B virus infection: A major concern in HIV-infected patients: Occult HBV in HIV
- PMID: 22087108
- PMCID: PMC3206662
Occult hepatitis B virus infection: A major concern in HIV-infected patients: Occult HBV in HIV
Abstract
Human immunodeficiency virus (HIV)- infected patients are at risk of acquiring viral hepatitis, due to common routes of transmission. As the introduction of highly active antiretroviral therapy (HAART) reduced the frequency of opportunistic infections and improved survival, viral hepatitis emerged as an important cause of morbidity and mortality in HIV-infected cases. Occult hepatitis B virus (HBV) infection is characterized by presence of HBV infection without detectable hepatitis B surface antigen (HBsAg). There are conflicting reports on the impact of occult HBV infection on the natural history of HIV disease. In this review, we described the findings of studies on HIV and hepatitis B co-infection with focus on the prevalence of occult HBV infection. The results of this review demonstrated the importance of prevention, diagnosis and treatment of occult HBV infection in HIV-positive patients.
Keywords: Hepatitis B virus; Hepatitis C virus; Human immunodeficiency virus.
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References
-
- WHO. Hepatitis B. Dublin: World Health Organization; 2004 [updated 2004;cited 06-10-2010]; Available from: http://who.int/inf-fs/en/fact204.html.
-
- Kew MC. Epidemiology of chronic hepatitis B virus infection, hepatocellular carcinoma, and hepatitis B virus-induced hepatocellular carcinoma. Pathol Biol (Paris). 2010;58(4):273–7. - PubMed
-
- de-Franchis R, Hadengue A, Lau G, Lavanchy D, Lok A, McIntyre N, Mele A, Paumgartner G, Pietrangelo A, Rodés J, Rosenberg W, Valla D, EASL J. EASL International Consensus Conference on Hepatitis B. 13-14 September, 2002 Geneva, Switzerland. Consensus statement (long version) J Hepatol. 2003;39:S3–25. - PubMed
-
- Alavian SM, Fallahian F, Lankarani KB. The changing epidemiology of viral hepatitis B in Iran. J Gastrointestin Liver Dis. 2007;16(4):403–6. - PubMed
-
- Andre F. Hepatitis B epidemiology in Asia, the Middle East and Africa. Vaccine. 2000;18((Suppl 1)):S20–2. - PubMed
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