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. 2011 Nov 16;4(1):16.
doi: 10.1186/1756-6614-4-16.

Coincidence of remission of postpartum Graves' disease and use of omega-3 fatty acid supplements

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Coincidence of remission of postpartum Graves' disease and use of omega-3 fatty acid supplements

Sarah J Breese McCoy. Thyroid Res. .

Abstract

I developed Graves' Disease four months postpartum. After one year on propylthiouracil, I learned that omega-3 fatty acids may reduce inflammation associated with certain autoimmune disorders, although no investigations for thyroiditis have been reported. Within eight weeks of beginning flaxseed oil supplements, TSH levels normalized, but fell somewhat when flaxseed was decreased and PTU discontinued. During another pregnancy, plasma TSH normalized, but was again suppressed by four weeks postpartum, then undetectable by four months. This time, flaxseed supplementation alone coincided with TSH normalization. Omega-3 fatty acids should be investigated as a potential treatment for autoimmune thyroid disease.

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References

    1. Zák A. [Pathophysiology of and clinical significance of polyunsaturated fatty acids n-3 family] Cas Lek Cesk. 2005;144(Suppl 1):6–18. - PubMed
    1. Simopoulos AP. Omega-3 fatty acids in inflammation and autoimmune diseases. J Am Coll Nutr. 2002;21:495–505. - PubMed
    1. Harbige LS. Dietary n-6 and n-3 fatty acids in immunity and autoimmune disease. Proc Nutr Soc. 1998;57:555–62. doi: 10.1079/PNS19980081. - DOI - PubMed
    1. Yaqoob P, Newsholme EA, Calder PC. Influence of cell culture conditions on diet-induced changes in lymphocyte fatty acid composition. Biochim Biophys Acta. 1995;1255:333–340. - PubMed
    1. Perterson LD, Jeffery NM, Thies F, Sanderson P, Newshoime EA, Calder PC. Eicosapentaenoic and docosahexaenoic acids alter rat spleen leukocyte fatty acid composition and prostaglandin E2 produciton but have different effects on lymphocyte functions and cell-mediated immunity. Lipids. 1998;33:171–180. doi: 10.1007/s11745-998-0193-y. - DOI - PubMed

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