Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2011 Oct 14;17(38):4308-13.
doi: 10.3748/wjg.v17.i38.4308.

High resolution colonoscopy in a bowel cancer screening program improves polyp detection

Matthew R Banks  1 , Rehan Haidry, M Adil Butt, Lisa Whitley, Judith Stein, Louise Langmead, Stuart L Bloom, Austin O'Bichere, Sara McCartney, Kalpesh Basherdas, Manuel Rodriguez-Justo, Laurence B Lovat
Affiliations

High resolution colonoscopy in a bowel cancer screening program improves polyp detection

Matthew R Banks et al. World J Gastroenterol. .

Abstract

Aim: To compare high resolution colonoscopy (Olympus Lucera) with a megapixel high resolution system (Pentax HiLine) as an in-service evaluation.

Methods: Polyp detection rates and measures of performance were collected for 269 colonoscopy procedures. Five colonoscopists conducted the study over a three month period, as part of the United Kingdom bowel cancer screening program.

Results: There were no differences in procedure duration (χ² P = 0.98), caecal intubation rates (χ² P = 0.67), or depth of sedation (χ² P = 0.64). Mild discomfort was more common in the Pentax group (χ² P = 0.036). Adenoma detection rate was significantly higher in the Pentax group (χ² test for trend P = 0.01). Most of the extra polyps detected were flat or sessile adenomas.

Conclusion: Megapixel definition colonoscopes improve adenoma detection without compromising other measures of endoscope performance. Increased polyp detection rates may improve future outcomes in bowel cancer screening programs.

Keywords: Bowel cancer screening; High resolution colonoscopy; Polyp detection.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Discomfort scores during colonoscopy. The degree of mild discomfort was worse for patients undergoing colonoscopy with Pentax scopes; however, there was no increase in moderate discomfort and no patients suffered severe discomfort with either scope.
Figure 2
Figure 2
Polyp detection rates. More polyps were found with Pentax HiLine colonoscopes than with Olympus Lucera colonoscopes. χ2 test for trend P = 0.01.
Figure 3
Figure 3
Sizes of polyps. Box plot demonstrating that the median size of polyps was identical for both hyperplastic and adenomatous polyps for both type of colonoscope. Median, interquartile range, and minimum and maximum polyp sizes are shown for each polyp type and colonoscope.
See this image and copyright information in PMC

References

    1. Common cancers - UK mortality statistics. Cancer Research UK. 2010 Available from: http://info.cancerresearchuk.org/cancerstats/mortality/cancerdeaths/
    1. Schrock TR. Colonoscopy versus barium enema in the diagnosis of colorectal cancers and polyps. Gastrointest Endosc Clin N Am. 1993;3:585–610.
    1. Rex DK, Cutler CS, Lemmel GT, Rahmani EY, Clark DW, Helper DJ, LehmanGA , Mark DG. Colonoscopic miss rates of adenomas determined by back-to-back colonoscopies. Gastroenterology. 1997;112:24–28. - PubMed
    1. Bressler B, Paszat LF, Chen Z, Rothwell DM, Vinden C, Rabeneck L. Rates of new or missed colorectal cancers after colonoscopy and their risk factors: a population-based analysis. Gastroenterology. 2007;132:96–102. - PubMed
    1. Kaminski MF, Regula J, Kraszewska E, Polkowski M, Wojciechowska U, Didkowska J, Zwierko M, Rupinski M, Nowacki MP, Butruk E. Quality indicators for colonoscopy and the risk of interval cancer. N Engl J Med. 2010;362:1795–1803. - PubMed

Publication types