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Randomized Controlled Trial
. 2012 Jan 15;54(2):253-6.
doi: 10.1093/cid/cir791. Epub 2011 Nov 17.

Ribosomal RNA evidence of ocular Chlamydia trachomatis infection following 3 annual mass azithromycin distributions in communities with highly prevalent trachoma

Jeremy D Keenan  1 , Berhan Ayele, Teshome Gebre, Jeanne Moncada, Nicole E Stoller, Zhaoxia Zhou, Travis C Porco, Charles E McCulloch, Bruce D Gaynor, Paul M Emerson, Julius Schachter, Thomas M Lietman
Affiliations
Randomized Controlled Trial

Ribosomal RNA evidence of ocular Chlamydia trachomatis infection following 3 annual mass azithromycin distributions in communities with highly prevalent trachoma

Jeremy D Keenan et al. Clin Infect Dis. .

Abstract

Twelve trachoma-hyperendemic communities were treated with 3 annual mass azithromycin distributions. Children aged 0-9 years were monitored 1 year following the third treatment. An RNA-based test detected ocular chlamydial infection in more children than did a DNA-based test (6.9% vs 4.2%), and in a larger number of communities (8 vs 7).

Trial registration: ClinicalTrials.gov NCT00322972.

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References

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