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. 2012 Feb;125(2):147-56.
doi: 10.1111/j.1600-0447.2011.01797.x. Epub 2011 Nov 19.

Predictors of persistence in girls with attention deficit hyperactivity disorder: results from an 11-year controlled follow-up study

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Predictors of persistence in girls with attention deficit hyperactivity disorder: results from an 11-year controlled follow-up study

J Biederman et al. Acta Psychiatr Scand. 2012 Feb.

Abstract

Objective: This study sought to examine the age-dependent persistence of attention deficit hyperactivity disorder (ADHD) and its predictors in a large sample of girls with and without ADHD followed prospectively for 11 years into young adulthood.

Method: Participants were girls with (N=96) and without (N=91) ADHD and were 6-17 years old at the baseline assessment (mean age, 11 years) and 15-30 years old at the follow-up assessment (mean: 22 years). Participants were comprehensively and blindly assessed with structured diagnostic interviews and assessments of cognitive, social, school, and family functioning.

Results: At the 11-year follow-up, 33.3% met full criteria for ADHD, 29.2% showed partial persistence of the disorder, 10.4% had impaired functioning, and 4.2% were remitted but treated (77.1% of the sample). Predictors of persistence were psychiatric comorbidity, family history of psychopathology, and family and school functioning at baseline.

Conclusion: These long-term, prospective, follow-up findings extend to girls findings that ADHD is persistent over the long term and can be predicted from psychosocial adversity and psychiatric comorbidity ascertained 11 years earlier.

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Figures

Fig. 1
Fig. 1
Persistence of ADHD at 11- year follow-up.
Fig. 2
Fig. 2
Age-specific prevalence of persistence of ADHD at the 11-year follow-up by definition of persistence and symptom type (N=92). The prevalence of persistence varied considerably depending on the definition used. Age was not significantly associated with any definition of persistence (all p>0.20).
Fig. 3
Fig. 3
CBCL at baseline

References

    1. Mannuzza S, Klein RG, Truong NL, Moulton JL, 3rd, Roizen ER, Howell KH, et al. Age of methylphenidate treatment initiation in children with ADHD and later substance abuse: prospective follow-up into adulthood. Am J Psychiatry. 2008;165:604–609. - PMC - PubMed
    1. Weiss G, Hechtman L, Milroy T, Perlman T. Psychiatric status of hyperactives as adults: a controlled prospective 15-year follow-up of 63 hyperactive children. Journal of the American Academy of Child and Adolescent Psychiatry. 1985;24:211–220. - PubMed
    1. Barkley RA, Fischer M. The unique contribution of emotional impulsiveness to impairment in major life activities in hyperactive children as adults. Journal of the American Academy of Child & Adolescent Psychiatry. 2010;49:503–513. - PubMed
    1. Satterfield JH, Faller KJ, Crinella FM, Schell AM, Swanson JM, Homer LD. A 30-year prospective follow-up study of hyperactive boys with conduct problems: adult criminality. J Am Acad Child Adolesc Psychiatry. 2007;46:601–610. - PubMed
    1. Fergusson DM, Boden JM, Horwood LJ. Classification of behavior disorders in adolescence: scaling methods, predictive validity, and gender differences. J Abnorm Psychol. 2010;119:699–712. - PubMed

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