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Case Reports
. 2011 Nov;17(11):2050-2.
doi: 10.3201/eid1711.110496.

Astrovirus MLB2 viremia in febrile child

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Case Reports

Astrovirus MLB2 viremia in febrile child

Lori R Holtz et al. Emerg Infect Dis. 2011 Nov.

Abstract

Astroviruses cause diarrhea, but it is not known whether they circulate in human plasma. Astrovirus MLB2 was recently discovered in diarrhea samples from children. We detected MLB2 in the plasma of a febrile child, which suggests that MLB2 has broader tropism than expected and disease potential beyond the gastrointestinal tract.

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Figures

Figure
Figure
Map of 10 plasma-derived astrovirus MLB2 strain contigs generated by high-throughput sequencing (Genome Analyzer IIX; Illumina Inc., San Diego, CA, USA). ORF, open reading frame.

References

    1. Walter JE, Mitchell DK. Astrovirus infection in children. Curr Opin Infect Dis. 2003;16:247–53. 10.1097/00001432-200306000-00011 - DOI - PubMed
    1. Finkbeiner SR, Allred AF, Tarr PI, Klein EJ, Kirkwood CD, Wang D. Metagenomic analysis of human diarrhea: viral detection and discovery. PLoS Pathog. 2008;4:e1000011. 10.1371/journal.ppat.1000011 - DOI - PMC - PubMed
    1. Finkbeiner SR, Holtz LR, Jiang Y, Rajendran P, Franz CJ, Zhao G, et al. Human stool contains a previously unrecognized diversity of novel astroviruses. Virol J. 2009;6:161. 10.1186/1743-422X-6-161 - DOI - PMC - PubMed
    1. Finkbeiner SR, Li Y, Ruone S, Conrardy C, Gregoricus N, Toney D, et al. Identification of a novel astrovirus (astrovirus VA1) associated with an outbreak of acute gastroenteritis. J Virol. 2009;83:10836–9. 10.1128/JVI.00998-09 - DOI - PMC - PubMed
    1. Kapoor A, Li L, Victoria J, Oderinde B, Mason C, Pandey P, et al. Multiple novel astrovirus species in human stool. J Gen Virol. 2009;90:2965–72. 10.1099/vir.0.014449-0 - DOI - PMC - PubMed

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