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. 2012 Jan;39(1):33-58.
doi: 10.1016/j.cps.2011.09.007.

Skin tissue engineering--in vivo and in vitro applications

Affiliations

Skin tissue engineering--in vivo and in vitro applications

Florian Groeber et al. Clin Plast Surg. 2012 Jan.

Erratum in

  • Clin Plast Surg. 2012 Apr;39(2):xi
  • Erratum.
    [No authors listed] [No authors listed] Clin Plast Surg. 2012 Apr;39(2):xi. doi: 10.1016/j.cps.2012.02.009. Epub 2012 Apr 4. Clin Plast Surg. 2012. PMID: 30029300 No abstract available.

Abstract

Significant progress has been made over the years in the development of in vitro-engineered substitutes that mimic human skin, either to be used as grafts for the replacement of lost skin or for the establishment of human-based in vitro skin models. This review summarizes these advances in in vivo and in vitro applications of tissue-engineered skin. We further highlight novel efforts in the design of complex disease-in-a-dish models for studies ranging from disease etiology to drug development and screening.

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