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Review
. 2012 Mar;164(1-2):43-5.
doi: 10.1016/j.virusres.2011.11.003. Epub 2011 Nov 11.

Cell tropism and entry of porcine circovirus 2

H J Nauwynck  1 , R Sanchez, P Meerts, D J Lefebvre, D Saha, L Huang, G Misinzo
Affiliations
Review

Cell tropism and entry of porcine circovirus 2

H J Nauwynck et al. Virus Res. 2012 Mar.

Abstract

Porcine circovirus 2 (PCV2) may induce reproductive failure (return to oestrus, embryonic death, mummification, weak- and stillborn piglets) and postweaning multisystemic wasting syndrome (PMWS). Furthermore, it may modulate the immunity in such a way that it aggravates the outcome of many bacterial and viral infections. In the present paper, the cellular tropism and entry of PCV2 are described and linked with the pathological and clinical consequences.

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