Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comparative Study
. 2012 Mar;33(2):273-8.
doi: 10.1016/j.cct.2011.11.010. Epub 2011 Nov 12.

Effectiveness of an informational video method to improve enrollment and retention of a pediatric cohort

Patricia Gesualdo  1 , Lisa Ide, Marian Rewers, Judith Baxter
Affiliations
Comparative Study

Effectiveness of an informational video method to improve enrollment and retention of a pediatric cohort

Patricia Gesualdo et al. Contemp Clin Trials. 2012 Mar.

Abstract

Objective: The Environmental Determinants of Diabetes in the Young (TEDDY), a multinational epidemiological study, is designed to identify environmental exposures triggering autoimmunity and type 1 diabetes (T1D) in children at increased genetic risk. The objective of this analysis was to evaluate the use of an informational video in the enrollment and retention of eligible participants at the Colorado TEDDY clinical center.

Study design and setting: Eligible participants were divided into two groups based on the inclusion of the video in the enrollment materials: the No-Video Group (n=449) did not receive the video and were contacted between 7/1/07 and 6/30/08. The Video Group (n=494) received the video and were contacted between 7/1/08 and 6/30/09. Multiple logistic regression compared the enrollment rates (percent of eligible subjects deciding to enroll) of those who received the video compared to those who did not. Kaplan-Meier survival analysis and a multivariate Cox proportional hazards model compared the differences in study retention, as defined by active participation fifteen months after the baseline visit at three months of age.

Results: Both groups were demographically similar. The enrollment rate was significantly higher for the Video Group (56.9%) compared to the No-Video Group (49.9%). Differences remained significant with adjustment for other known factors. A difference in retention between the two groups was not observed.

Conclusion: Methods and materials increasing understanding and more accurately informing participants of what is involved in participation may increase enrollment in a prospective observational study.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Comparison of Early Withdrawal Among the No-Video and Video Groups Colorado Center of the TEDDY Study
See this image and copyright information in PMC

References

    1. Ryan R, Prictor M, McLaughlin KJ, Hill S. Audio-visual presentation of information for informed consent for participation in clinical trials: Cochrane Database of Systematic Review. 2008;(Issue 1) Art No.: CD003717. DOI:10.1002/14651858.CD003717.pub2. - PubMed
    1. Jiminson HB, Sher PP, Appleyard R, LeVernois Y. The use of multimedia in the informed consent process. Journal of the American Informatics Association. 1998;5(3):245–56. - PMC - PubMed
    1. Du W, Mood D, Gadgeel SM. An educational video to increase clinical trials enrollment among breast cancer patients. Breast Cancer Research and Treatment. 2009:339–347. - PMC - PubMed
    1. Du W, Mood D, Gadgeel SM. An educational video to increase clinical trials enrollment among lung cancer patients. Journal of Thoracic Oncology. 2008;3(1):23–29. - PubMed
    1. Yates BC, Dondendorf D, Lane J, LaFramboise L, Pozehl B, Duncan K, Knodel K. Testing an Alternate Informed Consent Process. Nursing Research. 58(2):135–139. - PubMed

Publication types