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Case Reports
. 2011 Dec;84(1008):e226-8.
doi: 10.1259/bjr/15914752.

Case report. Acinar cell carcinoma with fatty change arising from the pancreas

Affiliations
Case Reports

Case report. Acinar cell carcinoma with fatty change arising from the pancreas

W-S Chung et al. Br J Radiol. 2011 Dec.

Abstract

Acinar cell carcinoma of the pancreas is a rare malignant tumour developing from acinar cells, accounting for approximately 1% of pancreatic exocrine tumours. We experienced a case of an acinar cell carcinoma with fatty change. To the best of our knowledge, this is the first case report of an acinar cell carcinoma with fatty change in the clinical literature.

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Figures

Figure 1
Figure 1
A 72-year-old female. (a) Contrast-enhanced CT showing a mass in the neck of the pancreas, which had less intense enhancement than the pancreas. (b) Axial T2 weighted MRI with fat suppression showed low signal intensity in this mass. (c) In-phase and (d) out-of-phase MRI showing a fat component in this mass.
Figure 2
Figure 2
Microscopic findings. (a) Pancreatic mass showing an acinar pattern of cells with nucleoli. The tumour cells with extensive and various degrees of clear cell change and fatty change (haematoxylin and eosin stain) (×100). (b) The tumour cells showed strong and diffuse immunoreactivity for alpha-fetoprotein (×200).

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