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Comment
. 2011 Nov;7(11):e1002381.
doi: 10.1371/journal.pgen.1002381. Epub 2011 Nov 10.

De novo origins of human genes

Daniele Guerzoni  1 , Aoife McLysaght
Affiliations
Comment

De novo origins of human genes

Daniele Guerzoni et al. PLoS Genet. 2011 Nov.
No abstract available

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Figure 1
Figure 1. Evidence in the detection of novel genes.
A hypothetical example where a novel human ORF is created by a human-specific deletion. The 1 bp deletion shifts a downstream stop codon out of frame. Because the deletion is not shared by other primates, the ancestral sequence is inferred to carry the in-frame stop. The authenticity of the novel human gene can be confirmed with transcription and translation evidence.
See this image and copyright information in PMC

Comment on

References

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