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. 1977 Nov;18(3):433-7.

Hemolytic activity of a lipid material obtained from peroxidized microsomes

  • PMID: 22110

Hemolytic activity of a lipid material obtained from peroxidized microsomes

R J Willis et al. Res Commun Chem Pathol Pharmacol. 1977 Nov.

Abstract

Lipid peroxidation was induced in rat liver microsomes by the addition of NADPH. When mixed with red cells in the presence of EDTA, these peroxidized microsomes caused hemolysis. All of the hemolytic activity of peroxidized microsomes could be extracted with lipid solvents and recovered as an aqueous lipid emulsion.

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