Role of inflammation in benign prostatic hyperplasia
- PMID: 22110398
- PMCID: PMC3221555
Role of inflammation in benign prostatic hyperplasia
Abstract
Inflammation of the prostate may represent a mechanism for hyperplastic changes to occur in the prostate. There are a variety of growth factors and cytokines that may lead to a proinflammatory process within the prostate. There are several proposed mechanisms that lead to both the intrinsic and extrinsic basis of inflammation. Prostatic inflammation may represent an important factor in influencing prostatic growth and progression of symptoms. This article reviews the recent literature on inflammation leading to chronic prostatic diseases, such as benign prostatic hyperplasia.
Keywords: Benign prostatic hyperplasia; Inflammation; Prostatic cytokines; Prostatitis; Vitamin D.
References
-
- McVary KT. BPH: epidemiology and comorbidities. Am J Manag Care. 2006;12(suppl 5):S122–S128. - PubMed
-
- Roehrborn CG. BPH progression: concept and key learning from MTOPS, ALTESS, COMBAT, and ALF-ONE. BJU Int. 2008;101(suppl 3):17–21. - PubMed
-
- Mishra VC, Allen DJ, Nicolaou C, et al. Does intraprostatic inflammation have a role in the pathogenesis and progression of benign prostatic hyperplasia? BJU Int. 2007;100:327–331. - PubMed
-
- Nickel JC. Prostatic inflammation in benign prostatic hyperplasia — the third component? Can J Urol. 1994;1:1–4. - PubMed
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