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. 2010 Jan;1(1):1-5.
doi: 10.4103/0976-237X.62510.

Oral manifestations of HIV

Smrati Bajpai  1 , A R Pazare
Affiliations

Oral manifestations of HIV

Smrati Bajpai et al. Contemp Clin Dent. 2010 Jan.

Abstract

The infection of the root canal system is considered to be a polymicrobial infection, consisting of both aerobic and anaerobic bacteria. Because of the complexity of the root canal infection, it is unlikely that any single antibiotic could result in effective sterilization of the canal. A combination of antibiotic drugs (metronidazole, ciprofloxacin, and minocycline) is used to eliminate target bacteria, which are possible sources of endodontic lesions. Three case reports describe the nonsurgical endodontic treatment of teeth with large periradicular lesions. A triple antibiotic paste was used for 3 months. After 3 months, teeth were asymptomatic and were obturated. The follow-up radiograph of all the three cases showed progressive healing of periradicular lesions. The results of these cases show that when most commonly used medicaments fail in eliminating the symptoms then a triple antibiotic paste can be used clinically in the treatment of teeth with large periradicular lesions.

Keywords: Ciprofloxacin; metronidazole; minocycline; nonsurgical root canal treatment; periradicular lesion; triple antibiotic paste.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1
Figure 1
Hyperplastic candidiasis
Figure 2
Figure 2
Pseudomembranous candidiasis
See this image and copyright information in PMC

References

    1. Grando LJ, Yurgel LS, Machado DC, Nachman S, Ferguson F, Berentsen B, et al. The association between oral manifestations and the socioeconomic and cultural characteristics of HIV-infected children in Brazil and in the United States of America. Rev Panam Salud Publica. 2003;14:112–8. - PubMed
    1. Ceballos-Salobreña A, Gaitán-Cepeda LA, Ceballos-Garcia L, Lezama-Del Valle D. Oral lesions in HIV/AIDS patients undergoing highly active antiretroviral treatment including protease inhibitors: A new face of oral AIDS? AIDS Patient Care STDS. 2000;14:627–35. - PubMed
    1. Interim WHO clinical staging of HIV/AIDS and HIV/AIDS case definitions for surveillance: WHO-HIV. 2005:2.
    1. Klein RS, Harris CA, Small CB, Moll B, Lesser M, Friedland GH. Oral candidiasis in high risk patients as the initial manifestation of the acquired immunodeficiency syndrome. N Engl J Med. 1984;311:354–8. - PubMed
    1. Silverman S, Jr, Migliorati CA, Lozada-Nur F, Greenspan D, Conant MA. Oral findings in people with or at risk for AIDS: A study of 375 homosexual males. J Am Dent Assoc. 1986;112:187–92. - PubMed