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Case Reports
. 2010 Jan;1(1):31-5.
doi: 10.4103/0976-237X.62519.

Nonsurgical healing of large periradicular lesions using a triple antibiotic paste: A case series

Sonali Taneja  1 , Manju Kumari, Hari Parkash
Affiliations
Case Reports

Nonsurgical healing of large periradicular lesions using a triple antibiotic paste: A case series

Sonali Taneja et al. Contemp Clin Dent. 2010 Jan.

Abstract

The infection of the root canal system is considered to be a polymicrobial infection, consisting of both aerobic and anaerobic bacteria. Because of the complexity of the root canal infection, it is unlikely that any single antibiotic could result in effective sterilization of the canal. A combination of antibiotic drugs (metronidazole, ciprofloxacin, and minocycline) is used to eliminate target bacteria, which are possible sources of endodontic lesions. Three case reports describe the nonsurgical endodontic treatment of teeth with large periradicular lesions. A triple antibiotic paste was used for 3 months. After 3 months, teeth were asymptomatic and were obturated. The follow-up radiograph of all the three cases showed progressive healing of periradicular lesions. The results of these cases show that when most commonly used medicaments fail in eliminating the symptoms then a triple antibiotic paste can be used clinically in the treatment of teeth with large periradicular lesions.

Keywords: Ciprofloxacin; metronidazole; minocycline; nonsurgical root canal treatment; periradicular lesion; triple antibiotic paste.

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Conflict of interest statement

Conflict of Interest: None declared.

Figures

Figure 1A
Figure 1A
Preoperative panoramic radiograph showing large peri-radicular lesion in left mandibular region
Figure 1B
Figure 1B
Healing seen 12 months after obturation
Figure 1C
Figure 1C
IOPA 16 months after obturation new
Figure 2A
Figure 2A
Preoperative panoramic radiograph showing large radiolucent lesion
Figure 2B
Figure 2B
Ten months after obturation
Figure 3A
Figure 3A
Preoperative IOPA showing large radiolucency in left mandibular region
Figure 3B
Figure 3B
IOPA showing healing seen 12 months after obturation
See this image and copyright information in PMC

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