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Review
. 2012 Jun;11(2):440-2.
doi: 10.1007/s12311-011-0329-3.

Cerebellar stimulation in ataxia

Stefan Jun Groiss  1 , Yoshikazu Ugawa
Affiliations
Review

Cerebellar stimulation in ataxia

Stefan Jun Groiss et al. Cerebellum. 2012 Jun.

Abstract

The cerebellum plays an important role in movement execution and motor control by modulation of the primary motor cortex (M1) through cerebello-thalamo-cortical connections. Transcranial magnetic stimulation (TMS) allows direct investigations of neural networks by stimulating neural structures in humans noninvasively. The motor evoked potential to single-pulse TMS of M1 is used to measure the motor cortical excitability. A conditioning stimulus over the cerebellum preceding a test stimulus of the contralateral M1 enables us to study the cerebellar regulatory functions on M1. In this brief review, we describe this cerebellar stimulation method and its usefulness as a diagnostic tool in clinical neurophysiology.

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