Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 2011 Nov 25;334(6059):1069-70.
doi: 10.1126/science.1215480.

Development. Inheriting maternal mtDNA

Beth Levine  1 , Zvulun Elazar
Affiliations
Comment

Development. Inheriting maternal mtDNA

Beth Levine et al. Science. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1. Selective autophagy of paternal mitochondria
(A) The C. elegans hermaphrodite reproductive tract is shown. (B) Fusion of sperm and oocyte in the C. elegans spermatheca transfers the paternal nucleus, membranous organelles (MOs), and mitochondria to the (C) cytoplasm of the fertilized oocyte. MOs in the vicinity of the paternal mitochondria are labeled with ubiquitin (Ub) chains for degradation. Both MOs and paternal mitochondria are selectively recruited to autophagosomes (LGG-1/2–labeled membranes), which fuse with lysosomes.
See this image and copyright information in PMC

Comment on

References

    1. Ankel-Simons F, Cummins JM. Proc. Natl. Acad. Sci. U.S.A. 1996;93:13859. - PMC - PubMed
    1. Sato M, Sato K. Science. 2011;334:1141. - PubMed
    1. Al Rawi S, et al. Science. 2011;334:1144. - PubMed
    1. Weidberg H, Shvets E, Elazar Z. Annu. Rev. Biochem. 2011;80:125. - PubMed
    1. Nishimura Y, et al. Proc. Natl. Acad. Sci. U.S.A. 2006;103:1382. - PubMed

Publication types

Substances