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Review
. 2011 Dec;61(6):297-301.
doi: 10.1111/j.1875-595X.2011.00072.x. Epub 2011 Nov 8.

Perspectives for the use of silver nanoparticles in dental practice

René García-Contreras  1 , Liliana Argueta-Figueroa, Cynthia Mejía-Rubalcava, Rocio Jiménez-Martínez, Sahamanta Cuevas-Guajardo, Paola Ariselda Sánchez-Reyna, Hugo Mendieta-Zeron
Affiliations
Review

Perspectives for the use of silver nanoparticles in dental practice

René García-Contreras et al. Int Dent J. 2011 Dec.

Abstract

Nanotechnology has been used for medical applications in several forms, including dental practice with the development of silver nanoparticles (Ag NPs) as a useful tool. The aim of this review was to identify the properties and appliances of Ag NPs in dental practice. Silver compounds and NPs have already been used as dental restorative material, endodontic retrofill cements, dental implants and caries inhibitory solution. Despite the effectiveness that Ag NPs has shown in dental practice, Ag NPs remain a controversial area of research with respect to their toxicity in biological and ecological systems. Therefore any application of Ag NPs in dentistry requires more studies. In order to avoid the toxicity of these materials Ag NPs can be temporarily used in dentistry.

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Figures

Figure 1.
Figure 1.
Scanning Electron Microscope views of Ag NPs. Illustration provided by Professor Raúl Alberto Morales Luckie, Faculty of Chemistry, UAEMex.
Figure 2.
Figure 2.
Cytotoxicity of Ag(NH3)F2 and AgCl against six cell lines, respectively. HPLF, human periodontal ligament fibroblast cells; HGF, human gingival fibroblast cells; HPC, human pulp cells and human oral squamous cells carcinoma obtained from different patients (HSC-2, 3, 4) were incubated for 24 h with the indicated concentrations of metal and then the relative viable cell number was determined by MTT method. Each value represents the mean±S.D. of triplicate assays. Reproducible results were obtained in further two independent experiments.
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