Keeping STATs on memory CD8+ T cells
- PMID: 22118521
- DOI: 10.1016/j.immuni.2011.11.006
Keeping STATs on memory CD8+ T cells
Abstract
The CD8(+) T cell response is characterized by generation of a population of effector cells and establishment of a persistent memory pool. In this issue, Cui et al. (2011) and Siegel et al. (2011) show that cytokine receptor signaling through the transcription factor STAT3 establishes stable memory CD8(+) T cells.
Copyright © 2011 Elsevier Inc. All rights reserved.
Comment on
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An interleukin-21-interleukin-10-STAT3 pathway is critical for functional maturation of memory CD8+ T cells.Immunity. 2011 Nov 23;35(5):792-805. doi: 10.1016/j.immuni.2011.09.017. Immunity. 2011. PMID: 22118527 Free PMC article.
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A critical role for STAT3 transcription factor signaling in the development and maintenance of human T cell memory.Immunity. 2011 Nov 23;35(5):806-18. doi: 10.1016/j.immuni.2011.09.016. Immunity. 2011. PMID: 22118528 Free PMC article.
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