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Comparative Study
. 2012 May;23(5):613-20.
doi: 10.1007/s00192-011-1616-8. Epub 2011 Nov 26.

Uniaxial biomechanical properties of seven different vaginally implanted meshes for pelvic organ prolapse

Jonathan P Shepherd  1 , Andrew J Feola, Steven D Abramowitch, Pamela A Moalli
Affiliations
Comparative Study

Uniaxial biomechanical properties of seven different vaginally implanted meshes for pelvic organ prolapse

Jonathan P Shepherd et al. Int Urogynecol J. 2012 May.

Abstract

Introduction and hypothesis: Recently, numerous type I macroporous polypropylene vaginal meshes have been introduced into the market with little known of their differences.

Methods: Seven vaginal meshes were obtained and loaded to failure (n = 5/type). Additional cyclic loading determined permanent deformation with submaximal loading.

Results: The load elongation curves demonstrated a bilinear response with lower stiffness (N/mm), followed by higher stiffness. Ascend™ was the stiffest mesh in both regions of the load elongation curve (0.72 and 1.66 N/mm) with the lowest transition to higher stiffness (13.4%). Polyform™ had the highest failure load (53.8 N) while Ultrapro™ had the lowest (7.83 N). Novasilk™ (89.4%) and Ultrapro™ (87.9%) had the highest relative elongations at mesh failure while Ascend™ had the lowest (40.2%). Ascend™ had the least relative elongation after three protocols of cyclic loading (3.0%, 9.8%, and 9.7%).

Conclusions: Current vaginal meshes demonstrate marked variation in biomechanical characteristics which may impact the in vivo behavior.

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Conflict of interest statement

Disclaimers, and Conflicts of Interest: None

Figures

Figure 1
Figure 1
Microscopic images with unique pattern and porosity of each mesh
Figure 2
Figure 2
Representative load-elongation curve after incremental load to failure
Figure 3
Figure 3
Representative load-elongation curve with submaximal cyclic loading
See this image and copyright information in PMC

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