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. 2011 Sep-Oct;56(5):533-6.
doi: 10.4103/0019-5154.87149.

Psoriasis and increased prevalence of hypertension and diabetes mellitus

Maryam Ghiasi  1 , Mohammad Nouri, Ata Abbasi, Parvaneh Hatami, Mohammad Amin Abbasi, Keramat Nourijelyani
Affiliations

Psoriasis and increased prevalence of hypertension and diabetes mellitus

Maryam Ghiasi et al. Indian J Dermatol. 2011 Sep-Oct.

Abstract

Background: Psoriasis is an autoimmune skin disease and associated with other diseases such as cardiovascular, hypertension, and diabetes mellitus.

Aim: Our aim was to explore the prevalence of diabetes mellitus and hypertension in psoriatic patients.

Materials and methods: Between April 2008 and May 2010, a total of 304 psoriatic and 300 nonpsoriatic patients were enrolled in this cross sectional study. Data were obtained on age, sex, weight, heights, etc; documented medical history of diabetes mellitus and hypertension; family history of diabetes mellitus and hypertension in first relatives, history of smoking.

Results: There was no significant difference in age and gender distribution between two groups. There was also no difference in body mass index between two groups. Within psoriatic group, 79.3% of patients present with plaque type of the disease and 20.7% present with other types. The results showed that within psoriatic patients, the prevalence of diabetes in women is significantly higher than in men (OR=1.93, CI95%: 1.1-3.6, P=0.004) but this difference is not present in nonpsoriatic patients. The results also showed that the prevalence of diabetes in psoriatic patients is significantly higher than nonpsoriatic patients (OR=1.76, CI95%: 1.11-2.8, P=0.015). The data showed that psoriatic patients were more likely to develop hypertension compared with nonpsoriatic patients (OR=2.2, CI95%: 1.2-4.6, P=0.003). According to results, although smoking rate within psoriatic patients is higher than the other group but the difference was not significant.

Conclusion: Psoriatic patients have an increased risk of developing metabolic syndrome and hypertension in comparison to nonpsoriatic patients.

Keywords: Diabetes mellitus; hypertension; psoriasis.

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Conflict of interest statement

Conflict of Interest: Nil.

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