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Review
. 2012 Mar;14(3):217-27.
doi: 10.1016/j.micinf.2011.11.001. Epub 2011 Nov 15.

A battle for iron: host sequestration and Staphylococcus aureus acquisition

Kathryn P Haley  1 , Eric P Skaar
Affiliations
Review

A battle for iron: host sequestration and Staphylococcus aureus acquisition

Kathryn P Haley et al. Microbes Infect. 2012 Mar.

Abstract

The use of iron as an enzymatic cofactor is pervasive in biological systems. Consequently most living organisms, including pathogenic bacteria, require iron to survive and replicate. To combat infection vertebrates have evolved sophisticated iron sequestration systems against which, pathogenic bacteria have concomitantly evolved equally elaborate iron acquisition mechanisms.

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Figure 1
Iron homeostasis in health and disease
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