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Case Reports
. 2011 Sep;2(3):319-22.
doi: 10.1159/000332424. Epub 2011 Sep 27.

Cystoid Macular Edema after Complicated Cataract Surgery Resolved by an Intravitreal Dexamethasone 0.7-mg Implant

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Case Reports

Cystoid Macular Edema after Complicated Cataract Surgery Resolved by an Intravitreal Dexamethasone 0.7-mg Implant

Linda M Meyer et al. Case Rep Ophthalmol. 2011 Sep.

Abstract

Purpose: To report the effective treatment of cystoid macular edema (CME) following complicated cataract surgery (resulting in Irvine-Gass syndrome) with a dexamethasone 0.7-mg (Ozurdex(®)) intravitreal implant.

Methods: An interventional case report with optical coherence tomography (OCT) scans.

Results: An 83-year-old Caucasian woman was suffering from CME following complicated cataract surgery on her left eye. She had undergone 3 intravitreal injections of dexamethasone 0.4 mg in the 3 months following the surgery without any improvement of visual function. Seven months after the cataract surgery, she received a single intravitreal injection of dexamethasone 0.7 mg (Ozurdex). Four weeks following the injection, her best-corrected visual acuity improved from 0.3 to 0.8. CME resolved with a reduction of central retinal thickness from 393 μm pre-Ozurdex injection to 212 μm post-Ozurdex injection, as measured by OCT scan.

Conclusion: Dexamethasone 0.7 mg (Ozurdex) has proven to be an effective treatment option in retinal vein occlusion and non-infectious uveitis. It can also be considered as off-label treatment in Irvine-Gass syndrome.

Keywords: Cystoid macular edema; Dexamethasone 0.7 mg; Irvine-Gass syndrome; Ozurdex®.

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Figures

Fig. 1
Fig. 1
OCT scan of CME following complicated cataract surgery. The infrared picture shows retinal localization. CME was refractory to treatment with 3 intravitreal injections of dexamethasone 0.4 mg. Central retinal thickness was 393 μm.
Fig. 2
Fig. 2
Resolved macular edema 4 weeks following an intravitreal injection of a dexamethasone 0.7-mg implant (Ozurdex). The infrared picture shows retinal localization. Central retinal thickness was 212 μm.
Fig. 3
Fig. 3
Follow-up examination 120 days after Ozurdex injection. The infrared picture shows retinal localization. Central retinal thickness was 210 μm.

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