Cystoid Macular Edema after Complicated Cataract Surgery Resolved by an Intravitreal Dexamethasone 0.7-mg Implant
- PMID: 22125533
- PMCID: PMC3220909
- DOI: 10.1159/000332424
Cystoid Macular Edema after Complicated Cataract Surgery Resolved by an Intravitreal Dexamethasone 0.7-mg Implant
Abstract
Purpose: To report the effective treatment of cystoid macular edema (CME) following complicated cataract surgery (resulting in Irvine-Gass syndrome) with a dexamethasone 0.7-mg (Ozurdex(®)) intravitreal implant.
Methods: An interventional case report with optical coherence tomography (OCT) scans.
Results: An 83-year-old Caucasian woman was suffering from CME following complicated cataract surgery on her left eye. She had undergone 3 intravitreal injections of dexamethasone 0.4 mg in the 3 months following the surgery without any improvement of visual function. Seven months after the cataract surgery, she received a single intravitreal injection of dexamethasone 0.7 mg (Ozurdex). Four weeks following the injection, her best-corrected visual acuity improved from 0.3 to 0.8. CME resolved with a reduction of central retinal thickness from 393 μm pre-Ozurdex injection to 212 μm post-Ozurdex injection, as measured by OCT scan.
Conclusion: Dexamethasone 0.7 mg (Ozurdex) has proven to be an effective treatment option in retinal vein occlusion and non-infectious uveitis. It can also be considered as off-label treatment in Irvine-Gass syndrome.
Keywords: Cystoid macular edema; Dexamethasone 0.7 mg; Irvine-Gass syndrome; Ozurdex®.
Figures



Similar articles
-
Intravitreal injection of dexamethasone implant and ranibizumab in cystoid macular edema in the course of irvine-gass syndrome.Case Rep Ophthalmol. 2014 Aug 4;5(2):243-8. doi: 10.1159/000365945. eCollection 2014 May. Case Rep Ophthalmol. 2014. PMID: 25232337 Free PMC article.
-
Radiation Macular Edema after Ru-106 Plaque Brachytherapy for Choroidal Melanoma Resolved by an Intravitreal Dexamethasone 0.7-mg Implant.Case Rep Ophthalmol. 2012 Jan;3(1):71-6. doi: 10.1159/000337144. Epub 2012 Feb 25. Case Rep Ophthalmol. 2012. PMID: 22529805 Free PMC article.
-
Fluocinolone Acetonide 0.19 mg Implant in Patients with Cystoid Macular Edema Due To Irvine-Gass Syndrome.Int Med Case Rep J. 2021 Feb 26;14:127-132. doi: 10.2147/IMCRJ.S295045. eCollection 2021. Int Med Case Rep J. 2021. PMID: 33664598 Free PMC article.
-
Dexamethasone intravitreal implant (OZURDEX®) for macular edema secondary to noninfectious uveitis: a review of the literature.Ther Deliv. 2019 Jun 1;10(6):343-351. doi: 10.4155/tde-2019-0024. Epub 2019 Jun 11. Ther Deliv. 2019. PMID: 31184554 Review.
-
Retinal vein occlusion and the use of a dexamethasone intravitreal implant (Ozurdex®) in its treatment.Graefes Arch Clin Exp Ophthalmol. 2016 Jul;254(7):1257-65. doi: 10.1007/s00417-016-3350-x. Epub 2016 May 13. Graefes Arch Clin Exp Ophthalmol. 2016. PMID: 27178087 Free PMC article. Review.
Cited by
-
Efficacy of intravitreal dexamethasone implant for prostaglandin-induced refractory pseudophakic cystoid macular edema: case report and review of the literature.Clin Ophthalmol. 2014 Jul 2;8:1253-7. doi: 10.2147/OPTH.S63829. eCollection 2014. Clin Ophthalmol. 2014. PMID: 25061272 Free PMC article.
-
Intravitreal Fluocinolone Acetonide Implant (FAc, 0.19 mg, ILUVIEN®) in the Treatment of Patients with Recurrent Cystoid Macular Edema After Pars Plana Vitrectomy.Ophthalmol Ther. 2023 Feb;12(1):377-388. doi: 10.1007/s40123-022-00613-9. Epub 2022 Nov 21. Ophthalmol Ther. 2023. PMID: 36417092 Free PMC article.
-
The role of Dexamethasone in clinical pharmaceutical treatment for patients with cataract surgery.Exp Ther Med. 2018 Feb;15(2):2177-2181. doi: 10.3892/etm.2017.5639. Epub 2017 Dec 15. Exp Ther Med. 2018. PMID: 29434822 Free PMC article.
-
Longstanding refractory pseudophakic cystoid macular edema resolved using intravitreal 0.7 mg dexamethasone implants.Clin Ophthalmol. 2013;7:1171-4. doi: 10.2147/OPTH.S46399. Epub 2013 Jun 13. Clin Ophthalmol. 2013. PMID: 23818753 Free PMC article.
-
Evaluation of pain during intravitreal Ozurdex injections vs. intravitreal bevacizumab injections.Eye (Lond). 2014 Aug;28(8):980-5. doi: 10.1038/eye.2014.129. Epub 2014 Jun 13. Eye (Lond). 2014. PMID: 24924442 Free PMC article.
References
-
- Arevalo JF, Maia M, Garcia-Amaris RA, Roca JA, Sanchez JG, Berrocal MH, L Wu, Pan-American Collaborative Retina Study Group Intravitreal bevacizumab for refractory pseudophakic cystoid macular edema: the Pan-American Collaborative Retina Study Group results. Ophthalmology. 2009;116:1481–1487. - PubMed
-
- Drolsum L, Haaskjold E. Causes of decreased visual acuity after cataract extraction. J Cataract Refract Surg. 1995;21:59–63. - PubMed
-
- Shelsta HN, Jampol LM. Pharmacologic therapy of pseudophakic cystoid macular edema: 2010 update. Retina. 2011;31:4–12. - PubMed
Publication types
LinkOut - more resources
Full Text Sources